MARTINS DOS SANTOS, V.A.P. and Jiří DAMBORSKÝ. Systems biology at work. Current Opinion in Biotechnology. Elsevier, 2010, vol. 21, No 21, p. 498-501. ISSN 0958-1669.
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Basic information
Original name Systems biology at work
Authors MARTINS DOS SANTOS, V.A.P. (276 Germany) and Jiří DAMBORSKÝ (203 Czech Republic, guarantor, belonging to the institution).
Edition Current Opinion in Biotechnology, Elsevier, 2010, 0958-1669.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10600 1.6 Biological sciences
Country of publisher Germany
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 8.486
RIV identification code RIV/00216224:14310/10:00040600
Organization unit Faculty of Science
UT WoS 000282717000010
Keywords (in Czech) Editorial overview; systems biology; engineering
Keywords in English Editorial overview; systems biology;engineering
Tags International impact, Reviewed
Changed by Changed by: prof. RNDr. Luděk Bláha, Ph.D., učo 15473. Changed: 14/2/2012 21:24.
Abstract
A core paradigm in systems biology is that biological systems are essentially built of highly coordinated sets of interacting networks across different scales [2]. Accordingly, biological behaviour can be thus described in terms of network properties and of their responses to internal and external perturbations, those being genetic, for example mutations, evolutionary rearrangement, or external, such as through the addition of chemicals or environmental changes.
Links
ED0001/01/01, research and development projectName: CETOCOEN
GAP202/10/1435, research and development projectName: Analýza a vizualizace proteinových struktur
Investor: Czech Science Foundation, Analysis and Visualization of Protein Structures
GA203/08/0114, research and development projectName: Specifické iontové efekty pro proteiny v roztocích a podobné biologicky relevantní systémy.
Investor: Czech Science Foundation, Specific ion effects for proteins in solutions and related biologically relevant systems
IAA401630901, research and development projectName: Evoluce substrátové specifity u enzymů aktivních s xenobiotickými látkami
Investor: Academy of Sciences of the Czech Republic, Evolution of substrate specificity in enzymes acting on xenobiotic compounds
LC06010, research and development projectName: Centrum biokatalýzy a biotransformací
Investor: Ministry of Education, Youth and Sports of the CR, Center of Biocatalysis and Biotransformation
MSM0021622412, plan (intention)Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)
Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)
MSM0021622413, plan (intention)Name: Proteiny v metabolismu a při interakci organismů s prostředím
Investor: Ministry of Education, Youth and Sports of the CR, Proteins in metabolism and interaction of organisms with the environment
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