J 2010

Systems biology at work

MARTINS DOS SANTOS, V.A.P. and Jiří DAMBORSKÝ

Basic information

Original name

Systems biology at work

Authors

MARTINS DOS SANTOS, V.A.P. (276 Germany) and Jiří DAMBORSKÝ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Current Opinion in Biotechnology, Elsevier, 2010, 0958-1669

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10600 1.6 Biological sciences

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 8.486

RIV identification code

RIV/00216224:14310/10:00040600

Organization unit

Faculty of Science

UT WoS

000282717000010

Keywords (in Czech)

Editorial overview; systems biology; engineering

Keywords in English

Editorial overview; systems biology;engineering

Tags

International impact, Reviewed
Změněno: 14/2/2012 21:24, prof. RNDr. Luděk Bláha, Ph.D.

Abstract

V originále

A core paradigm in systems biology is that biological systems are essentially built of highly coordinated sets of interacting networks across different scales [2]. Accordingly, biological behaviour can be thus described in terms of network properties and of their responses to internal and external perturbations, those being genetic, for example mutations, evolutionary rearrangement, or external, such as through the addition of chemicals or environmental changes.

Links

ED0001/01/01, research and development project
Name: CETOCOEN
GAP202/10/1435, research and development project
Name: Analýza a vizualizace proteinových struktur
Investor: Czech Science Foundation, Analysis and Visualization of Protein Structures
GA203/08/0114, research and development project
Name: Specifické iontové efekty pro proteiny v roztocích a podobné biologicky relevantní systémy.
Investor: Czech Science Foundation, Specific ion effects for proteins in solutions and related biologically relevant systems
IAA401630901, research and development project
Name: Evoluce substrátové specifity u enzymů aktivních s xenobiotickými látkami
Investor: Academy of Sciences of the Czech Republic, Evolution of substrate specificity in enzymes acting on xenobiotic compounds
LC06010, research and development project
Name: Centrum biokatalýzy a biotransformací
Investor: Ministry of Education, Youth and Sports of the CR, Center of Biocatalysis and Biotransformation
MSM0021622412, plan (intention)
Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)
Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)
MSM0021622413, plan (intention)
Name: Proteiny v metabolismu a při interakci organismů s prostředím
Investor: Ministry of Education, Youth and Sports of the CR, Proteins in metabolism and interaction of organisms with the environment