Detailed Information on Publication Record
2010
Arabidopsis PIS1 encodes the ABCG37 transporter of auxinic compounds including the auxin precursor indole-3-butyric acid.
RŮŽIČKA, K., L. C. STRADER, A. BAILLY, H. YANG, J. BLAKESLEE et. al.Basic information
Original name
Arabidopsis PIS1 encodes the ABCG37 transporter of auxinic compounds including the auxin precursor indole-3-butyric acid.
Authors
RŮŽIČKA, K. (203 Czech Republic), L. C. STRADER (840 United States of America), A. BAILLY (840 United States of America), H. YANG (410 Republic of Korea), J. BLAKESLEE (840 United States of America), Ł. ŁANGOWSKI (616 Poland), Eliška NEJEDLÁ (203 Czech Republic, belonging to the institution), H. FUJITA (392 Japan), H. ITOH (392 Japan), K. SYONO (392 Japan), Jan HEJÁTKO (203 Czech Republic, belonging to the institution), W .M. GRAY (840 United States of America), E. MARTINOIA (756 Switzerland), M. GEISLER (756 Switzerland), B. BARTEL (840 United States of America), A. MURPHY (840 United States of America) and Jiří FRIML (203 Czech Republic, guarantor, belonging to the institution)
Edition
Proceedings of the National Academy of Sciences of the U.S.A., 2010, 0027-8424
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
Genetics and molecular biology
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 9.771
RIV identification code
RIV/00216224:14310/10:00045665
Organization unit
Faculty of Science
UT WoS
000278549300075
Keywords in English
pdr9; pdr8; iba transport; auxin synthesis
Změněno: 28/4/2011 14:49, RNDr. Eliška Nejedlá, CSc.
Abstract
V originále
Cellular auxin levels are determined by processes including synthesis, degradation, and conjugation, as well as by auxin transport across the plasma membrane. Whereas transport of free auxins such as naturally occurring IAA is well characterized, little is known about the transport of auxin precursors and metabolites. Here, we identify amutation in the ABCG37 gene of Arabidopsis that causes the polar auxin transport inhibitor sensitive1 (pis1) phenotype manifested by hypersensitivity to auxinic compounds. ABCG37 encodes the pleiotropic drug resistance transporter that transports a range of synthetic auxinic compounds as well as the endogenous auxin precursor indole-3-butyric acid (IBA), but not free IAA. ABCG37 and its homolog ABCG36 act redundantly at outermost root plasma membranes and, unlike established IAA transporters from the PIN and ABCB families, transport IBA out of the cells. Our findings explore possible novel modes of regulating auxin homeostasis and plant development.
Links
MSM0021622415, plan (intention) |
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