| RŮŽIČKA, K., L. C. STRADER, A. BAILLY, H. YANG, J. BLAKESLEE, Ł. ŁANGOWSKI, Eliška NEJEDLÁ, H. FUJITA, H. ITOH, K. SYONO, Jan HEJÁTKO, W .M. GRAY, E. MARTINOIA, M. GEISLER, B. BARTEL, A. MURPHY and Jiří FRIML. Arabidopsis PIS1 encodes the ABCG37 transporter of auxinic compounds including the auxin precursor indole-3-butyric acid. Proceedings of the National Academy of Sciences of the U.S.A.,. 2010, vol. 107, No 23, p. 10749-10753. ISSN 0027-8424. |
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@article{911193,
author = {Růžička, K. and Strader, L. C. and Bailly, A. and Yang, H. and Blakeslee, J. and Łangowski, Ł. and Nejedlá, Eliška and Fujita, H. and Itoh, H. and Syono, K. and Hejátko, Jan and Gray, W .M. and Martinoia, E. and Geisler, M. and Bartel, B. and Murphy, A. and Friml, Jiří},
article_number = {23},
keywords = {pdr9; pdr8; iba transport; auxin synthesis},
language = {eng},
issn = {0027-8424},
journal = {Proceedings of the National Academy of Sciences of the U.S.A.,},
title = {Arabidopsis PIS1 encodes the ABCG37 transporter of auxinic compounds including the auxin precursor indole-3-butyric acid.},
volume = {107},
year = {2010}
}
TY - JOUR
ID - 911193
AU - Růžička, K. - Strader, L. C. - Bailly, A. - Yang, H. - Blakeslee, J. - Łangowski, Ł. - Nejedlá, Eliška - Fujita, H. - Itoh, H. - Syono, K. - Hejátko, Jan - Gray, W .M. - Martinoia, E. - Geisler, M. - Bartel, B. - Murphy, A. - Friml, Jiří
PY - 2010
TI - Arabidopsis PIS1 encodes the ABCG37 transporter of auxinic compounds including the auxin precursor indole-3-butyric acid.
JF - Proceedings of the National Academy of Sciences of the U.S.A.,
VL - 107
IS - 23
SP - 10749-10753
EP - 10749-10753
SN - 00278424
KW - pdr9
KW - pdr8
KW - iba transport
KW - auxin synthesis
N2 - Cellular auxin levels are determined by processes including synthesis, degradation, and conjugation, as well as by auxin transport across the plasma membrane. Whereas transport of free auxins such as naturally occurring IAA is well characterized, little is known about the transport of auxin precursors and metabolites. Here, we identify amutation in the ABCG37 gene of Arabidopsis that causes the polar auxin transport inhibitor sensitive1 (pis1) phenotype manifested by hypersensitivity to auxinic compounds. ABCG37 encodes the pleiotropic drug resistance transporter that transports a range of synthetic auxinic compounds as well as the endogenous auxin precursor indole-3-butyric acid (IBA), but not free IAA. ABCG37 and its homolog ABCG36 act redundantly at outermost root plasma membranes and, unlike established IAA transporters from the PIN and ABCB families, transport IBA out of the cells. Our findings explore possible novel modes of regulating auxin homeostasis and plant development.
ER -
RŮŽIČKA, K., L. C. STRADER, A. BAILLY, H. YANG, J. BLAKESLEE, Ł. ŁANGOWSKI, Eliška NEJEDLÁ, H. FUJITA, H. ITOH, K. SYONO, Jan HEJÁTKO, W .M. GRAY, E. MARTINOIA, M. GEISLER, B. BARTEL, A. MURPHY and Jiří FRIML. Arabidopsis PIS1 encodes the ABCG37 transporter of auxinic compounds including the auxin precursor indole-3-butyric acid. \textit{Proceedings of the National Academy of Sciences of the U.S.A.,}. 2010, vol.~107, No~23, p.~10749-10753. ISSN~0027-8424.
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