| BASALLOTE, Manuel G., Carmen E. CASTILLO, M. Angeles MÁÑEZ, Přemysl LUBAL, Manuel MARTÍNEZ, Carlos RODRÍGUEZ and Jakub VANĚK. Striking medium effects on the kinetics of decomposition of macrocyclic Cu(II) complexes: Additional considerations to be taken when designing Copper-64 radiopharmaceuticals. Inorganic Chemistry Communications. Netherlands: Elsevier Science, 2010, vol. 13, No 11, p. 1272-1274. ISSN 1387-7003. |
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@article{916085,
author = {Basallote, Manuel G. and Castillo, Carmen E. and Máñez, M. Angeles and Lubal, Přemysl and Martínez, Manuel and Rodríguez, Carlos and Vaněk, Jakub},
article_location = {Netherlands},
article_number = {11},
keywords = {Decomposition of copper complexes; Kinetics; Electrolyte media; Copper-64 radiopharmaceuticals},
language = {eng},
issn = {1387-7003},
journal = {Inorganic Chemistry Communications},
title = {Striking medium effects on the kinetics of decomposition of macrocyclic Cu(II) complexes: Additional considerations to be taken when designing Copper-64 radiopharmaceuticals},
url = {http://linkinghub.elsevier.com/retrieve/pii/S1387700310003084},
volume = {13},
year = {2010}
}
TY - JOUR
ID - 916085
AU - Basallote, Manuel G. - Castillo, Carmen E. - Máñez, M. Angeles - Lubal, Přemysl - Martínez, Manuel - Rodríguez, Carlos - Vaněk, Jakub
PY - 2010
TI - Striking medium effects on the kinetics of decomposition of macrocyclic Cu(II) complexes: Additional considerations to be taken when designing Copper-64 radiopharmaceuticals
JF - Inorganic Chemistry Communications
VL - 13
IS - 11
SP - 1272-1274
EP - 1272-1274
PB - Elsevier Science
SN - 13877003
KW - Decomposition of copper complexes
KW - Kinetics
KW - Electrolyte media
KW - Copper-64 radiopharmaceuticals
UR - http://linkinghub.elsevier.com/retrieve/pii/S1387700310003084
N2 - The kinetics of decomposition of a macrocyclic Cu2+ complex is strongly dependent on the anions in solution. In particular, chloride anions accelerate significantly the decomposition process, even out of the stopped-flow time scale. Given the different chloride concentrations in biological media, the possibility of changes in the decomposition kinetics must be considered when designing 64Cu radiopharmaceuticals.
ER -
BASALLOTE, Manuel G., Carmen E. CASTILLO, M. Angeles MÁÑEZ, Přemysl LUBAL, Manuel MARTÍNEZ, Carlos RODRÍGUEZ and Jakub VANĚK. Striking medium effects on the kinetics of decomposition of macrocyclic Cu(II) complexes: Additional considerations to be taken when designing Copper-64 radiopharmaceuticals. \textit{Inorganic Chemistry Communications}. Netherlands: Elsevier Science, 2010, vol.~13, No~11, p.~1272-1274. ISSN~1387-7003.
|
