J 2010

EFNS guidelines for the diagnosis and management of Alzheimers disease

HORT, J., JT. O BRIEN, G. GAINOTTI, T. PIRTTILA, BO. POPESCU et. al.

Basic information

Original name

EFNS guidelines for the diagnosis and management of Alzheimers disease

Name in Czech

EFNS doporučení pro diagnostiku a léčbu Alzheimerovy nemoci

Authors

HORT, J. (203 Czech Republic), JT. O BRIEN (826 United Kingdom of Great Britain and Northern Ireland), G. GAINOTTI (380 Italy), T. PIRTTILA (246 Finland), BO. POPESCU (642 Romania), Irena REKTOROVÁ (203 Czech Republic, belonging to the institution), S. SORBI (380 Italy) and P. SCHELTENS (528 Netherlands, guarantor)

Edition

European Journal of Neurology, 2010, 1351-5101

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 3.765

RIV identification code

RIV/00216224:14110/10:00047014

Organization unit

Faculty of Medicine

UT WoS

000281799200006

Keywords in English

Alzheimers disease; dementia; diagnosis; guideline; management; review; treatment
Změněno: 20/1/2011 23:28, prof. MUDr. Irena Rektorová, Ph.D.

Abstract

V originále

The aim of this revised international guideline was to present a peer-reviewed evidence-based statement for the guidance of practice for clinical neurologists, geriatricians, psychiatrists, and other specialist physicians responsible for the care of patients with AD. Mild cognitive impairment and non- Alzheimer dementias are not included in this guideline. Methods: The task force working group reviewed evidence from original research articles, meta-analysis, and systematic reviews, published before May 2009. The evidence was classified and consensus recommendations graded (A, B, or C) according to the EFNS guidance. Where there was a lack of evidence, but clear consensus, good practice points were provided. Results: The recommendations for clinical diagnosis, blood tests, neuropsychology, neuroimaging, electroencephalography, cerebrospinal fluid (CSF) analysis, genetic testing, disclosure of diagnosis, treatment of AD, behavioural and psychological symptoms in dementia, legal issues, counselling and support for caregivers were all revised as compared with the previous EFNS guideline. Conclusion: A number of new recommendations and good practice points are made, namely in CSF, neuropsychology, neuroimaging and reviewing non-evidence based therapies. The assessment, interpretation, and treatment of symptoms, disability, needs, and caregiver stress during the course of AD require the contribution of many different professionals. These professionals should adhere to these guideline to improve the diagnosis and management of AD.

Links

MSM0021622404, plan (intention)
Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.