HORT, J., JT. O BRIEN, G. GAINOTTI, T. PIRTTILA, BO. POPESCU, Irena REKTOROVÁ, S. SORBI and P. SCHELTENS. EFNS guidelines for the diagnosis and management of Alzheimers disease. European Journal of Neurology. 2010, vol. 17, No 10, p. 1236-1248. ISSN 1351-5101.
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Basic information
Original name EFNS guidelines for the diagnosis and management of Alzheimers disease
Name in Czech EFNS doporučení pro diagnostiku a léčbu Alzheimerovy nemoci
Authors HORT, J. (203 Czech Republic), JT. O BRIEN (826 United Kingdom of Great Britain and Northern Ireland), G. GAINOTTI (380 Italy), T. PIRTTILA (246 Finland), BO. POPESCU (642 Romania), Irena REKTOROVÁ (203 Czech Republic, belonging to the institution), S. SORBI (380 Italy) and P. SCHELTENS (528 Netherlands, guarantor).
Edition European Journal of Neurology, 2010, 1351-5101.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 3.765
RIV identification code RIV/00216224:14110/10:00047014
Organization unit Faculty of Medicine
UT WoS 000281799200006
Keywords in English Alzheimers disease; dementia; diagnosis; guideline; management; review; treatment
Changed by Changed by: prof. MUDr. Irena Rektorová, Ph.D., učo 26922. Changed: 20/1/2011 23:28.
Abstract
The aim of this revised international guideline was to present a peer-reviewed evidence-based statement for the guidance of practice for clinical neurologists, geriatricians, psychiatrists, and other specialist physicians responsible for the care of patients with AD. Mild cognitive impairment and non- Alzheimer dementias are not included in this guideline. Methods: The task force working group reviewed evidence from original research articles, meta-analysis, and systematic reviews, published before May 2009. The evidence was classified and consensus recommendations graded (A, B, or C) according to the EFNS guidance. Where there was a lack of evidence, but clear consensus, good practice points were provided. Results: The recommendations for clinical diagnosis, blood tests, neuropsychology, neuroimaging, electroencephalography, cerebrospinal fluid (CSF) analysis, genetic testing, disclosure of diagnosis, treatment of AD, behavioural and psychological symptoms in dementia, legal issues, counselling and support for caregivers were all revised as compared with the previous EFNS guideline. Conclusion: A number of new recommendations and good practice points are made, namely in CSF, neuropsychology, neuroimaging and reviewing non-evidence based therapies. The assessment, interpretation, and treatment of symptoms, disability, needs, and caregiver stress during the course of AD require the contribution of many different professionals. These professionals should adhere to these guideline to improve the diagnosis and management of AD.
Links
MSM0021622404, plan (intention)Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.
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