J 2010

Healing of Large Segmental Bone Defect after Implantation of Autogenous Cancellous Bone Graft in Comparison to Hydroxyapatite and 0.5% Collagen Scaffold Combined with Mesenchymal Stem Cells

NEČAS, Alois, Pavel PROKS, Lucie URBANOVÁ, Robert SRNEC, Ladislav STEHLÍK et. al.

Basic information

Original name

Healing of Large Segmental Bone Defect after Implantation of Autogenous Cancellous Bone Graft in Comparison to Hydroxyapatite and 0.5% Collagen Scaffold Combined with Mesenchymal Stem Cells

Name in Czech

Hojení segmentálního defektu kosti po implantaci autogenního spongiózního kostního štěpu ve srovnání se skafoldem z hydroxyapatitu a 0,5 % kolagenu v kombinaci s mezenchymovými kmenovými buňkami

Name (in English)

Healing of Large Segmental Bone Defect after Implantation of Autogenous Cancellous Bone Graft in Comparison to Hydroxyapatite and 0.5% Collagen Scaffold Combined with Mesenchymal Stem Cells

Authors

NEČAS, Alois (203 Czech Republic, guarantor, belonging to the institution), Pavel PROKS (203 Czech Republic, belonging to the institution), Lucie URBANOVÁ (203 Czech Republic, belonging to the institution), Robert SRNEC (203 Czech Republic), Ladislav STEHLÍK (203 Czech Republic), Michal CRHA (203 Czech Republic, belonging to the institution), Petr RAUŠER (203 Czech Republic, belonging to the institution), Ladislav PLÁNKA (203 Czech Republic, belonging to the institution), Jan JANOVEC (203 Czech Republic), Milan DVOŘÁK (203 Czech Republic), Evžen AMLER (203 Czech Republic, belonging to the institution), Lucy VOJTOVÁ (203 Czech Republic, belonging to the institution) and Josef JANČÁŘ (203 Czech Republic, belonging to the institution)

Edition

Acta Veterinaria, Brno, VETERINARNI A FARMACEUTICKA UNIVERZITA B, 2010, 0001-7213

Other information

Language

Czech

Type of outcome

Článek v odborném periodiku

Field of Study

30211 Orthopaedics

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 0.534

RIV identification code

RIV/00216224:14110/10:00047573

Organization unit

Faculty of Medicine

UT WoS

000287418300013

Keywords in English

Fracture fixation; bone healing; comminuted fracture; callus; ostectomy; buttress plate
Změněno: 17/3/2011 03:00, prof. MUDr. Ladislav Plánka, Ph.D.

Abstract

ORIG EN

V originále

No significant difference was found in the size of callus between animals of group S and animals of group S + MSCs. Unlike a scaffold in the shape of the original bone column, a freely placed autogenous cancellous bone graft may allow the newly formed tissue to spread more to the periphery of the ostectomy defect. Implanted cylindrical scaffolds (with and without MSCs) support callus formation directly in the center of original bone column in segmental femoral ostectomy, and can be successfully used in the treatment of large bone defects.

In English

No significant difference was found in the size of callus between animals of group S and animals of group S + MSCs. Unlike a scaffold in the shape of the original bone column, a freely placed autogenous cancellous bone graft may allow the newly formed tissue to spread more to the periphery of the ostectomy defect. Implanted cylindrical scaffolds (with and without MSCs) support callus formation directly in the center of original bone column in segmental femoral ostectomy, and can be successfully used in the treatment of large bone defects.

Links

2B06130, research and development project
Name: Využití nově syntetizovaných biomateriálů v kombinaci s kmenovými buňkami v léčbě chorob, které postihují lidské tkáně derivované z mesodermu: chrupavku, kost, vazy a menisky. (Acronym: Chondros)
Investor: Ministry of Education, Youth and Sports of the CR