NEČAS, Alois, Pavel PROKS, Lucie URBANOVÁ, Robert SRNEC, Ladislav STEHLÍK, Michal CRHA, Petr RAUŠER, Ladislav PLÁNKA, Jan JANOVEC, Milan DVOŘÁK, Evžen AMLER, Lucy VOJTOVÁ and Josef JANČÁŘ. Healing of Large Segmental Bone Defect after Implantation of Autogenous Cancellous Bone Graft in Comparison to Hydroxyapatite and 0.5% Collagen Scaffold Combined with Mesenchymal Stem Cells. Acta Veterinaria. Brno: VETERINARNI A FARMACEUTICKA UNIVERZITA B, 2010, vol. 79, No 4, p. 607-612. ISSN 0001-7213.
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Basic information
Original name Healing of Large Segmental Bone Defect after Implantation of Autogenous Cancellous Bone Graft in Comparison to Hydroxyapatite and 0.5% Collagen Scaffold Combined with Mesenchymal Stem Cells
Name in Czech Hojení segmentálního defektu kosti po implantaci autogenního spongiózního kostního štěpu ve srovnání se skafoldem z hydroxyapatitu a 0,5 % kolagenu v kombinaci s mezenchymovými kmenovými buňkami
Name (in English) Healing of Large Segmental Bone Defect after Implantation of Autogenous Cancellous Bone Graft in Comparison to Hydroxyapatite and 0.5% Collagen Scaffold Combined with Mesenchymal Stem Cells
Authors NEČAS, Alois (203 Czech Republic, guarantor, belonging to the institution), Pavel PROKS (203 Czech Republic, belonging to the institution), Lucie URBANOVÁ (203 Czech Republic, belonging to the institution), Robert SRNEC (203 Czech Republic), Ladislav STEHLÍK (203 Czech Republic), Michal CRHA (203 Czech Republic, belonging to the institution), Petr RAUŠER (203 Czech Republic, belonging to the institution), Ladislav PLÁNKA (203 Czech Republic, belonging to the institution), Jan JANOVEC (203 Czech Republic), Milan DVOŘÁK (203 Czech Republic), Evžen AMLER (203 Czech Republic, belonging to the institution), Lucy VOJTOVÁ (203 Czech Republic, belonging to the institution) and Josef JANČÁŘ (203 Czech Republic, belonging to the institution).
Edition Acta Veterinaria, Brno, VETERINARNI A FARMACEUTICKA UNIVERZITA B, 2010, 0001-7213.
Other information
Original language Czech
Type of outcome Article in a journal
Field of Study 30211 Orthopaedics
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.534
RIV identification code RIV/00216224:14110/10:00047573
Organization unit Faculty of Medicine
UT WoS 000287418300013
Keywords in English Fracture fixation; bone healing; comminuted fracture; callus; ostectomy; buttress plate
Changed by Changed by: prof. MUDr. Ladislav Plánka, Ph.D., učo 20583. Changed: 17/3/2011 03:00.
Abstract
No significant difference was found in the size of callus between animals of group S and animals of group S + MSCs. Unlike a scaffold in the shape of the original bone column, a freely placed autogenous cancellous bone graft may allow the newly formed tissue to spread more to the periphery of the ostectomy defect. Implanted cylindrical scaffolds (with and without MSCs) support callus formation directly in the center of original bone column in segmental femoral ostectomy, and can be successfully used in the treatment of large bone defects.
Abstract (in English)
No significant difference was found in the size of callus between animals of group S and animals of group S + MSCs. Unlike a scaffold in the shape of the original bone column, a freely placed autogenous cancellous bone graft may allow the newly formed tissue to spread more to the periphery of the ostectomy defect. Implanted cylindrical scaffolds (with and without MSCs) support callus formation directly in the center of original bone column in segmental femoral ostectomy, and can be successfully used in the treatment of large bone defects.
Links
2B06130, research and development projectName: Využití nově syntetizovaných biomateriálů v kombinaci s kmenovými buňkami v léčbě chorob, které postihují lidské tkáně derivované z mesodermu: chrupavku, kost, vazy a menisky. (Acronym: Chondros)
Investor: Ministry of Education, Youth and Sports of the CR
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