J 2010

Combined exposure to cyanobacterial biomass, lead and the Newcastle virus enhances avian toxicity

PIKULA, Jiří, Hana BANĎOUCHOVÁ, Klára HILSCHEROVÁ, Veronika PAŠKOVÁ, Jana SEDLÁČKOVÁ et. al.

Basic information

Original name

Combined exposure to cyanobacterial biomass, lead and the Newcastle virus enhances avian toxicity

Authors

PIKULA, Jiří (203 Czech Republic, guarantor), Hana BANĎOUCHOVÁ (203 Czech Republic), Klára HILSCHEROVÁ (203 Czech Republic, belonging to the institution), Veronika PAŠKOVÁ (203 Czech Republic, belonging to the institution), Jana SEDLÁČKOVÁ (203 Czech Republic), Ondřej ADAMOVSKÝ (203 Czech Republic, belonging to the institution), Zora KNOTKOVÁ (203 Czech Republic), Petr LANÝ (203 Czech Republic), Jiří MACHÁT (203 Czech Republic, belonging to the institution), Blahoslav MARŠÁLEK (203 Czech Republic, belonging to the institution), Ladislav NOVOTNÝ (203 Czech Republic), Miroslav POHANKA (203 Czech Republic) and František VITULA (203 Czech Republic)

Edition

Science of the Total Environment, AMSTERDAM, NETHERLANDS, ELSEVIER SCIENCE BV, 2010, 0048-9697

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10511 Environmental sciences

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 3.190

RIV identification code

RIV/00216224:14310/10:00052042

Organization unit

Faculty of Science

DOI

UT WoS

000282348100010

Keywords in English

Multiple stressors; Birds; Japanese quail model; Microcystin; Heavy metals; Sublethal exposure

Tags

Změněno: 20/4/2012 10:14, Ing. Andrea Mikešková

Abstract

V originále

This experimental study was successful in testing the hypothesis that adverse effects of cyanotoxins, heavy metals and a non-pathogenic immunological challenge combine to enhance avian toxicity. Mortality occurred in combined exposures to naturally occurring cyanobacterial biomass and lead shots, lead shots and Newcastle vaccination as well as in single lead shot exposure. Mostly acute effects around day 10 were observed. On day 30 of exposure, there were no differences in the liver accumulation of lead in single and combined exposure groups. Interestingly, liver microcystin levels were elevated in birds co-exposed to cyanobacterial biomass together with lead or lead and the Newcastle virus. Significant differences in body weights between all Pb-exposed and Pb-non-exposed birds were found on days 10 and 20. Single exposure to cyanobacterial biomass resulted in hepatic vacuolar dystrophy, whereas co-exposure with lead led to more severe granular dystrophy. Haematological changes were associated with lead exposure, in particular. Biochemical analysis revealed a decrease in glucose and an increase in lactate dehydrogenase in single and combined cyanobacterial and lead exposures, which also showed a decreased antibody response to vaccination.

Links

MSM0021622412, plan (intention)
Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)
Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)