J 2011

Association of eNOS gene polymorphisms T-786C and G894T with blood pressure variability in man

JÍRA, Miroslav, Eva ZÁVODNÁ, Nataša HONZÍKOVÁ, Zuzana NOVÁKOVÁ, Anna VAŠKŮ et. al.

Basic information

Original name

Association of eNOS gene polymorphisms T-786C and G894T with blood pressure variability in man

Name in Czech

Asociace polymorfismů T-786C a G894T v genu pro eNOS s variabilitou v krevním tlaku u člověka

Authors

JÍRA, Miroslav (203 Czech Republic, belonging to the institution), Eva ZÁVODNÁ (203 Czech Republic, belonging to the institution), Nataša HONZÍKOVÁ (203 Czech Republic, guarantor, belonging to the institution), Zuzana NOVÁKOVÁ (203 Czech Republic, belonging to the institution), Anna VAŠKŮ (203 Czech Republic, belonging to the institution), Lydie IZAKOVIČOVÁ HOLLÁ (203 Czech Republic, belonging to the institution) and Bohumil FIŠER (203 Czech Republic, belonging to the institution)

Edition

Physiological Research, Prague, Inst. Physiol., Acad. Sci. Czech Rep. 2011, 0862-8408

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30105 Physiology

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 1.555

RIV identification code

RIV/00216224:14110/11:00052087

Organization unit

Faculty of Medicine

UT WoS

000288563800020

Keywords (in Czech)

Variabilita v krevním tlaku;spektrální analýza; syntáza oxidu dusnatého; genetika; polymorfismus

Keywords in English

Arterial blood pressure variability; Spectral analysis; Nitric oxide synthase; Genetics; Polymorphism

Tags

International impact
Změněno: 12/4/2012 09:07, Mgr. Michal Petr

Abstract

V originále

The aim of this study was to evaluate the association of polymorphisms T-786C and G894T in the gene encoding eNOS with blood pressure variability (BPV) in man. In conclusion, the haplotype formed by less frequent alleles of both eNOS variants was associated with increased systolic and diastolic BPV in this study.

In Czech

Cílem studie bylo vyhodnotit asociaci polymorfismů T-786C a G894T v genu pro eNOS s variabilitou v krevním tlaku (VTK) u člověka. Haplotypy kombinované méně četnými alelami obou polymorfismů byly asociovány se zvýšenou variabilitou v krevním tlaku.

Links

MSM0021622402, plan (intention)
Name: Časná diagnostika a léčba kardiovaskulárních chorob
Investor: Ministry of Education, Youth and Sports of the CR, Early diagnostics and treatment of cardiovascular diseases