Detailed Information on Publication Record
2011
Gene polymorphisms in gingivitis
IZAKOVIČOVÁ HOLLÁ, Lydie, Kristína MUSILOVÁ, Jan VOKURKA, Pavla PANTUČKOVÁ, Lubomír KUKLA et. al.Basic information
Original name
Gene polymorphisms in gingivitis
Name in Czech
Genové polymorfizmy u gingivitidy
Authors
IZAKOVIČOVÁ HOLLÁ, Lydie (203 Czech Republic, guarantor, belonging to the institution), Kristína MUSILOVÁ (203 Czech Republic, belonging to the institution), Jan VOKURKA (203 Czech Republic, belonging to the institution), Pavla PANTUČKOVÁ (203 Czech Republic, belonging to the institution), Lubomír KUKLA (203 Czech Republic, belonging to the institution), Martina KUKLETOVÁ (203 Czech Republic, belonging to the institution) and Zdeněk BROUKAL (203 Czech Republic, belonging to the institution)
Edition
1. vydání. Rijeka, Gingival Diseases - Their Aetiology, Prevention and Treatment, p. 203-230, 28 pp. 2011
Publisher
INTECH
Other information
Language
English
Type of outcome
Kapitola resp. kapitoly v odborné knize
Field of Study
30200 3.2 Clinical medicine
Country of publisher
Croatia
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
RIV identification code
RIV/00216224:14110/11:00052207
Organization unit
Faculty of Medicine
ISBN
978-953-307-376-7
Keywords (in Czech)
gingivitida; genový polymorfizmus; parodontitida; zánět; děti
Keywords in English
gingivitis; gene polymorphism; periodontitis; inflammation; children
Tags
Reviewed
Změněno: 15/4/2012 11:23, Mgr. Michal Petr
Abstract
V originále
1) We aimed to conduct a review of the literature for gene polymorphisms associated with susceptibility to gingivitis. We searched the studies in English language using the key words gingivitis and gene (mutation or polymorphism) and analyzed their results. (a) Firstly, in introduction, etiopathogenesis and clinical picture of gingivitis were discussed, the role of genetics in this disease was analyzed and different approaches for genetic studies described. (b) Secondly, candidate genes in relation to gingivitis were analyzed and discussed in relation to various carriage rates of the rare (R)-allele, different environmental and other risk factors. 2) In addition, new data (still unpublished) about the role of interleukin-18 (IL-18) gene polymorphisms at positions -607C/A (rs1946518), -137G/C (rs187238) and -133C/G (rs360721) in relation to gingivitis and microbial pathogens in Czech children are presented in this chapter.
Links
NT11405, research and development project |
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1M0528, research and development project |
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