The seasonal changes in innate immunity of the common carp
(Cyprinus carpio)

J 2011

The seasonal changes in innate immunity of the common carp (Cyprinus carpio)

TOLAROVÁ, Soňa; Andrea VETEŠNÍKOVÁ ŠIMKOVÁ; Karolína ROHLENOVÁ; Martin FLAJŠHANS; Antonín LOJEK et. al.

Základní údaje

Originální název

The seasonal changes in innate immunity of the common carp (Cyprinus carpio)

Autoři

TOLAROVÁ, Soňa (203 Česká republika, domácí); Andrea VETEŠNÍKOVÁ ŠIMKOVÁ (703 Slovensko, domácí); Karolína ROHLENOVÁ (203 Česká republika, domácí); Martin FLAJŠHANS (203 Česká republika); Antonín LOJEK (203 Česká republika, domácí); Esa-Matti LILIUS (246 Finsko) a Pavel HYRŠL (203 Česká republika, garant, domácí)

Vydání

Aquaculture, 2011, 0044-8486

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30102 Immunology

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.041

Kód RIV

RIV/00216224:14310/11:00049795

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1016/j.aquaculture.2011.05.013

UT WoS

000292616000026

Klíčová slova anglicky

Cyprinus carpio; respiratory burst; phagocytes; complement; innate immunity; 11-ketotestosterone

Štítky

AKR, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 20. 4. 2012 10:23, Ing. Andrea Mikešková

Anotace

V originále

The innate immune response in fishes includes both cellular (phagocytes) and humoral (complement system mainly) components. In fish, as in mammals, reactive oxygen metabolites (ROM) are involved in the respiratory burst of phagocytes and three pathways of complement activation can be discerned. The aim of this study was to analyze the innate immune response of fish using parameters such as respiratory burst of phagocytes and the complement activity of plasma of the common carp (Cyprinus carpio, Cyprinidae). Samples from a total of 160 individuals were collected in five periods of the year (early summer, late summer, autumn, winter and spring). Respiratory burst activity of a constant blood volume was measured luminometrically also calculated per phagocyte number. A trend of negative relation between respiratory burst activity and water temperature was observed, thus the respiratory activity reached the lowest values in summer. Total complement activity of plasma was determined as bacteriolytic activity against bioluminescent bacteria. The highest total complement activity was observed in autumn, it decreased in summer and winter and the lowest activity was detected in spring. The highest activity of alternative pathway of complement activation was detected in spring, which decreased in autumn and the lowest values were found in winter and in summer. To evaluate the effect of steroid hormones, the level of 11-ketotestosterone was analyzed in males and the maximum was found in spring. A negative correlation was found between 11-ketotestosterone and both respiratory burst and total complement activity. Our results indicate that the measured parameters of innate immunity in the common carp are strongly affected by seasonal changes. Moreover, we confirmed that the innate immune response is immuno-suppressed by 11-ketotestosterone in spring.

Návaznosti

GA524/07/0188, projekt VaV

Název: Úloha imunitní investice v kontextu kompromisů: imunoekologické studium vztahů mezi reprodukcí, imunitou a parazitizmem u sladkovodních ryb

Investor: Grantová agentura ČR, Úloha imunitní investice v kontextu kompromisů: imunoekologické studium vztahů mezi reprodukcí, imunitou a parazitizmem u sladkovodních ryb

Citovat

TOLAROVÁ, Soňa; Andrea VETEŠNÍKOVÁ ŠIMKOVÁ; Karolína ROHLENOVÁ; Martin FLAJŠHANS; Antonín LOJEK; Esa-Matti LILIUS a Pavel HYRŠL. The seasonal changes in innate immunity of the common carp (Cyprinus carpio). Aquaculture. 2011, roč. 318, 1-2, s. 169-175. ISSN 0044-8486. Dostupné z: https://dx.doi.org/10.1016/j.aquaculture.2011.05.013.

@article{938536,
   author = {Tolarová, Soňa and Vetešníková Šimková, Andrea and Rohlenová, Karolína and Flajšhans, Martin and Lojek, Antonín and Lilius, EsaandMatti and Hyršl, Pavel},
   article_number = {1-2},
   doi = {http://dx.doi.org/10.1016/j.aquaculture.2011.05.013},
   keywords = {Cyprinus carpio; respiratory burst; phagocytes; complement; innate immunity; 11-ketotestosterone},
   language = {eng},
   issn = {0044-8486},
   journal = {Aquaculture},
   title = {The seasonal changes in innate immunity of the common carp (Cyprinus carpio)},
   volume = {318},
   year = {2011}
}

TY  - JOUR
ID  - 938536
AU  - Tolarová, Soňa - Vetešníková Šimková, Andrea - Rohlenová, Karolína - Flajšhans, Martin - Lojek, Antonín - Lilius, Esa-Matti - Hyršl, Pavel
PY  - 2011
TI  - The seasonal changes in innate immunity of the common carp (Cyprinus carpio)
JF  - Aquaculture
VL  - 318
IS  - 1-2
SP  - 169-175
EP  - 169-175
SN  - 00448486
KW  - Cyprinus carpio
KW  - respiratory burst
KW  - phagocytes
KW  - complement
KW  - innate immunity
KW  - 11-ketotestosterone
N2  - The innate immune response in fishes includes both cellular (phagocytes) and humoral (complement system mainly) components. In fish, as in mammals, reactive oxygen metabolites (ROM) are involved in the respiratory burst of phagocytes and three pathways of complement activation can be discerned. The aim of this study was to analyze the innate immune response of fish using parameters such as respiratory burst of phagocytes and the complement activity of plasma of the common carp (Cyprinus carpio, Cyprinidae). Samples from a total of 160 individuals were collected in five periods of the year (early summer, late summer, autumn, winter and spring). Respiratory burst activity of a constant blood volume was measured luminometrically also calculated per phagocyte number. A trend of negative relation between respiratory burst activity and water temperature was observed, thus the respiratory activity reached the lowest values in summer. Total complement activity of plasma was determined as bacteriolytic activity against bioluminescent bacteria. The highest total complement activity was observed in autumn, it decreased in summer and winter and the lowest activity was detected in spring. The highest activity of alternative pathway of complement activation was detected in spring, which decreased in autumn and the lowest values were found in winter and in summer. To evaluate the effect of steroid hormones, the level of 11-ketotestosterone was analyzed in males and the maximum was found in spring. A negative correlation was found between 11-ketotestosterone and both respiratory burst and total complement activity. Our results indicate that the measured parameters of innate immunity in the common carp are strongly affected by seasonal changes. Moreover, we confirmed that the innate immune response is immuno-suppressed by 11-ketotestosterone in spring.
ER  -

TOLAROVÁ, Soňa; Andrea VETEŠNÍKOVÁ ŠIMKOVÁ; Karolína ROHLENOVÁ; Martin FLAJŠHANS; Antonín LOJEK; Esa-Matti LILIUS a Pavel HYRŠL. The seasonal changes in innate immunity of the common carp (Cyprinus carpio). \textit{Aquaculture}. 2011, roč.~318, 1-2, s.~169-175. ISSN~0044-8486. Dostupné z: https://dx.doi.org/10.1016/j.aquaculture.2011.05.013.

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