GAD antibodies in T1D and LADA - relation to age, BMI,
C-peptide, IA-2and HLA DRB1*03 AND DRB1*04 alleles

J 2011

GAD antibodies in T1D and LADA - relation to age, BMI, C-peptide, IA-2and HLA DRB103 AND DRB104 alleles

WEBER, Pavel, Petronela AMBROŠOVÁ, Petr CANOV, Dana WEBEROVÁ, Pavel KUKLÍNEK et. al.

Basic information

Original name

GAD antibodies in T1D and LADA - relation to age, BMI, C-peptide, IA-2and HLA DRB1*03 AND DRB1*04 alleles

Name in Czech

GAD protilátek v T1D a LADA - vzhledem k věku, BMI, C-peptid, IA-2and HLA DRB1 * 03 a DRB1 * 04

Authors

WEBER, Pavel (203 Czech Republic, guarantor, belonging to the institution), Petronela AMBROŠOVÁ (703 Slovakia, belonging to the institution), Petr CANOV (203 Czech Republic, belonging to the institution), Dana WEBEROVÁ (203 Czech Republic, belonging to the institution), Pavel KUKLÍNEK (203 Czech Republic, belonging to the institution), Hana MELUZÍNOVÁ (203 Czech Republic, belonging to the institution) and Hana MATĚJOVSKÁ KUBEŠOVÁ (203 Czech Republic, belonging to the institution)

Edition

Advances in Gerontology / Uspekhi Gerontologii, 2011, 1561-9125

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

Russian Federation

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/11:00052473

Organization unit

Faculty of Medicine

Keywords in English

GAD antibodies; diabetes mellitus

Změněno: 2/2/2013 17:02, prof. MUDr. Pavel Weber, CSc.

Abstract

ORIG CZ

V originále

The determination of GADA may be useful for clinical classification of diabetes mellitus(DM) in clinically unclear cases. This GADA positivity may in any diabetics Type 1 diabetes Mellitus (T1D) with an onset in adulthood and Late Autoimmune Diabetes of Adults(LADA) persist many years after appearance of DM. The study was aimed at comparing the levels of GADA between both diabetic subsets with their clinical parameters, age of onset DM, perod of insulin need, body mass index, HbA1C, fasting and postprandial C-peptide, risky HLA-DRB1* alleles, occurrence of micro-and macrovascular diabetic complications.

In Czech

Stanovení GADA mohou být užitečné pro klinické klasifikaci diabetes mellitus (DM) v klinicky nejasných případech. Tato pozitivita GADA může v každém diabetiků 1. typu diabetes mellitus (T1D) s nástupem v dospělosti a pozdní autoimunitní diabetes dospělých (LADA) přetrvávat mnoho let po výskytu DM. Studie byla zaměřena na srovnání úrovně GADA obou diabetických podskupin s jejich klinickými parametry, věk nástupu DM, period inzulínu potřeba, index tělesné hmotnosti, HbA1C, nalačno a po jídle C-peptid, rizikové HLA-DRB1 * alel, výskyt mikro-a makrovaskulárních komplikací diabetu.

Citovat

WEBER, Pavel, Petronela AMBROŠOVÁ, Petr CANOV, Dana WEBEROVÁ, Pavel KUKLÍNEK, Hana MELUZÍNOVÁ and Hana MATĚJOVSKÁ KUBEŠOVÁ. GAD antibodies in T1D and LADA - relation to age, BMI, C-peptide, IA-2and HLA DRB1*03 AND DRB1*04 alleles (LADA antibodies in T1D and LADA - relation to age, BMI, C-peptide, IA-2and HLA DRB1*03 AND DRB1*04 alleles). Advances in Gerontology / Uspekhi Gerontologii. 2011, vol. 24, No 2, p. 312-318. ISSN 1561-9125.

@article{941837,
   author = {Weber, Pavel and Ambrošová, Petronela and Canov, Petr and Weberová, Dana and Kuklínek, Pavel and Meluzínová, Hana and Matějovská Kubešová, Hana},
   article_number = {2},
   keywords = {GAD antibodies; diabetes mellitus},
   language = {eng},
   issn = {1561-9125},
   journal = {Advances in Gerontology / Uspekhi Gerontologii},
   title = {GAD antibodies in T1D and LADA - relation to age, BMI, C-peptide, IA-2and HLA DRB1*03 AND DRB1*04 alleles},
   volume = {24},
   year = {2011}
}

TY  - JOUR
ID  - 941837
AU  - Weber, Pavel - Ambrošová, Petronela - Canov, Petr - Weberová, Dana - Kuklínek, Pavel - Meluzínová, Hana - Matějovská Kubešová, Hana
PY  - 2011
TI  - GAD antibodies in T1D and LADA - relation to age, BMI, C-peptide, IA-2and HLA DRB1*03 AND DRB1*04 alleles
JF  - Advances in Gerontology / Uspekhi Gerontologii
VL  - 24
IS  - 2
SP  - 312-318
EP  - 312-318
SN  - 15619125
KW  - GAD antibodies
KW  - diabetes mellitus
N2  - The determination of GADA may be useful for clinical classification of diabetes mellitus(DM) in clinically unclear cases. This GADA positivity may in any diabetics Type 1 diabetes Mellitus (T1D) with an onset in adulthood and Late Autoimmune Diabetes of Adults(LADA) persist many years after appearance of DM. The study was aimed at comparing the levels of GADA between both diabetic subsets with their clinical parameters, age of onset DM, perod of insulin need, body mass index, HbA1C, fasting and postprandial C-peptide, risky HLA-DRB1* alleles, occurrence of micro-and macrovascular diabetic complications.
ER  -

WEBER, Pavel, Petronela AMBROŠOVÁ, Petr CANOV, Dana WEBEROVÁ, Pavel KUKLÍNEK, Hana MELUZÍNOVÁ and Hana MATĚJOVSKÁ KUBEŠOVÁ. GAD antibodies in T1D and LADA - relation to age, BMI, C-peptide, IA-2and HLA DRB1*03 AND DRB1*04 alleles (LADA antibodies in T1D and LADA - relation to age, BMI, C-peptide, IA-2and HLA DRB1*03 AND DRB1*04 alleles). \textit{Advances in Gerontology / Uspekhi Gerontologii}. 2011, vol.~24, No~2, p.~312-318. ISSN~1561-9125.

Detailed Information on Publication Record