ČEŠKOVÁ, Eva. Deprese u schizofrenní poruchy (Depression in schizophrenia). Česká a slovenská psychiatrie. Praha: ČLS JEP, 2011, vol. 107, No 3, p. 155-159. ISSN 1212-0383. |
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Basic information | |
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Original name | Deprese u schizofrenní poruchy |
Name in Czech | Deprese u schizofrenní poruchy |
Name (in English) | Depression in schizophrenia |
Authors | ČEŠKOVÁ, Eva (203 Czech Republic, guarantor, belonging to the institution). |
Edition | Česká a slovenská psychiatrie, Praha, ČLS JEP, 2011, 1212-0383. |
Other information | |
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Original language | Czech |
Type of outcome | Article in a journal |
Field of Study | 30000 3. Medical and Health Sciences |
Country of publisher | Czech Republic |
Confidentiality degree | is not subject to a state or trade secret |
RIV identification code | RIV/00216224:14740/11:00052661 |
Organization unit | Central European Institute of Technology |
Keywords (in Czech) | deprese; schizofrenie; výskyt; léčba |
Keywords in English | depression; schizophrenia; occurrence; treatment |
Tags | ok, rivok |
Changed by | Changed by: prof. MUDr. Eva Češková, CSc., učo 726. Changed: 8/7/2011 08:02. |
Abstract |
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Článek shrnuje údaje o výskytu deprese u schizofrenního onemocnění s důrazem na první epizody. Přítomnost deprese u schizofrenie je spojena s horším průběhem a prognózou a zvýšeným rizikem suiciálního jednání, proto je důležitá včasná láčba. ATP 1. generace jsou spojována s rozvoje deprese, u ATP 2. generace se nevylučuje přímá antidepresivní aktivita. Další častou léčebnou strategií u depresivní symptomatologie u schizofrenní poruchy je augmentace antidepresivy. Dosavadní studie ukazují, že tento postup po odeznění akutní fáze je úspěšný a riziko rozvoje psychotické symptomatologie je minimální. |
Abstract (in English) |
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At first data concerning the occurrence of depression in schizophrenia, primarily focused on first-episode schizophrenia, are summarized. The presence of depression in schizophrenia is associated with a worse course and prognosis and increased risk of suicidal behaviour, therefore an early treatment is important. Antipsychotics of the first generation are associated with the development of depression, on the other site antipsychotics of the second generation may have a direct antidepressant activity. The further treatment strategy for depressive symptoms in schizophrenia includes antipsychotics augmentation with antidepressants. The available studies show that after the acute phase this approach is successful with minimal risk for development of psychotic symptoms. |
Links | |
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MSM0021622404, plan (intention) | Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS |
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions. |
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