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@article{945516, author = {Čupera, Jakub and Lánský, Petr}, article_number = {416}, doi = {http://dx.doi.org/10.1016/j.ijpharm.2011.05.081}, keywords = {Dissolution; Sigmoidal profile; Random lag time; Dissolution variability}, language = {eng}, issn = {0378-5173}, journal = {International Journal of Pharmaceutics}, title = {Homogeneous diffusion layer model of dissolution incorporating the initial transient phase}, url = {http://dx.doi.org/10.1016/j.ijpharm.2011.05.081}, volume = {2011}, year = {2011} }
TY - JOUR ID - 945516 AU - Čupera, Jakub - Lánský, Petr PY - 2011 TI - Homogeneous diffusion layer model of dissolution incorporating the initial transient phase JF - International Journal of Pharmaceutics VL - 2011 IS - 416 SP - 35-42 EP - 35-42 SN - 03785173 KW - Dissolution KW - Sigmoidal profile KW - Random lag time KW - Dissolution variability UR - http://dx.doi.org/10.1016/j.ijpharm.2011.05.081 L2 - http://dx.doi.org/10.1016/j.ijpharm.2011.05.081 N2 - We considered random lag time before the homogeneous phase of the dissolution begins. The resulting dissolution profiles are characterized by sigmoidal shape commonly observed in empirical dissolution data. Furthermore, probability distribution of repeated measurements at fixed time is deduced from the model and function describing variability of the data in dependency on time is proposed. ER -
ČUPERA, Jakub and Petr LÁNSKÝ. Homogeneous diffusion layer model of dissolution incorporating the initial transient phase. \textit{International Journal of Pharmaceutics}. 2011, vol.~2011, No~416, p.~35-42. ISSN~0378-5173. Available from: https://dx.doi.org/10.1016/j.ijpharm.2011.05.081.
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