Everything started in June 2007, when six Czech medical faculties agreed on cooperation in the fi eld of electronic teaching support and e-learning. The cooperation was based on more or less voluntary basis and all introductory activities were arising exclusively from passion of several enthusiasts. Now let us move approximately three and half years ahead into November 2010. The project MEFANET (MEdical FAculties NETwork) now involves eleven Czech and Slovak medical faculties and representatives of all members are getting together in the Brno hotel Voroněž to attend the fourth year of the MEFANET annual conference. The whole project is under the offi cial auspices of an agreement signed by deans of all faculties and supported by the European Social Fund in the Czech Republic. This short statement explicitly illustrates the way the MEFANET network has been growing up and acquiring importance and reputation. Nevertheless, let us shift from austere data to the traditional conference, which took place, as usually, in excellent atmosphere and brought lots of interesting topics and contributions.