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@article{946675, author = {Hrdličková, Barbara and Izakovičová Hollá, Lydie}, article_number = {10}, doi = {http://dx.doi.org/10.1016/j.humimm.2011.07.309}, keywords = {Allergic asthma; ORMDL3; single nucleotide polymorphism; SNP}, language = {eng}, issn = {0198-8859}, journal = {Human Immunology}, title = {Relationship between 17q21 locus and adult asthma in Czech population}, volume = {72}, year = {2011} }
TY - JOUR ID - 946675 AU - Hrdličková, Barbara - Izakovičová Hollá, Lydie PY - 2011 TI - Relationship between 17q21 locus and adult asthma in Czech population JF - Human Immunology VL - 72 IS - 10 SP - 921-925 EP - 921-925 PB - Elsevier SN - 01988859 KW - Allergic asthma KW - ORMDL3 KW - single nucleotide polymorphism KW - SNP N2 - Several whole-genome association studies have shown a significant link between childhood asthma and the 17q12 chromosome region. We selected tagging single nucleotide polymorphisms (SNPs) in the ORMDL3 gene (17q12) to investigate gene variability in relation to adult allergic asthma and asthma/atopy traits in the Czech Caucasians. Our findings suggest that the genetic variability in the 17q21 region may be one of the risk factors also for adult asthma, especially in males. ER -
HRDLIČKOVÁ, Barbara and Lydie IZAKOVIČOVÁ HOLLÁ. Relationship between 17q21 locus and adult asthma in Czech population. \textit{Human Immunology}. Elsevier, 2011, vol.~72, No~10, p.~921-925. ISSN~0198-8859. Available from: https://dx.doi.org/10.1016/j.humimm.2011.07.309.
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