BARNAT, Jiří, Luboš BRIM, Adam KREJČÍ, Adam STRECK, David ŠAFRÁNEK, Martin VEJNÁR and Tomáš VEJPUSTEK. On Parameter Synthesis by Parallel Model Checking. IEEE/ACM Transactions on Computational Biology and Bioinformatics. Los Alamitos: IEEE Computer Society, 2012, vol. 9, No 3, p. 693-705. ISSN 1545-5963. Available from: https://dx.doi.org/10.1109/TCBB.2011.110.
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Basic information
Original name On Parameter Synthesis by Parallel Model Checking
Authors BARNAT, Jiří (203 Czech Republic, belonging to the institution), Luboš BRIM (203 Czech Republic, belonging to the institution), Adam KREJČÍ (203 Czech Republic, belonging to the institution), Adam STRECK (203 Czech Republic, belonging to the institution), David ŠAFRÁNEK (203 Czech Republic, guarantor, belonging to the institution), Martin VEJNÁR (203 Czech Republic, belonging to the institution) and Tomáš VEJPUSTEK (203 Czech Republic, belonging to the institution).
Edition IEEE/ACM Transactions on Computational Biology and Bioinformatics, Los Alamitos, IEEE Computer Society, 2012, 1545-5963.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10201 Computer sciences, information science, bioinformatics
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 1.616
RIV identification code RIV/00216224:14330/12:00057196
Organization unit Faculty of Informatics
Doi http://dx.doi.org/10.1109/TCBB.2011.110
UT WoS 000301293900006
Keywords in English biological networks; parallel model checking; dynamical systems; parameter synthesis; systems biology
Tags International impact, Reviewed
Changed by Changed by: doc. RNDr. David Šafránek, Ph.D., učo 3159. Changed: 11/4/2013 17:34.
Abstract
An important problem in current computational systems biology is to analyse models of biological systems dynamics under parameter uncertainty. This paper presents a novel algorithm for parameter synthesis based on parallel model checking. The algorithm is conceptually universal with respect to the modelling approach employed. We introduce the algorithm, show its scalability, and examine its applicability on several biological models.
Links
GA201/09/1389, research and development projectName: Verifikace a analýza velmi velkých počítačových systémů
Investor: Czech Science Foundation, Verification and Analysis of Large-Scale Computer Systems
MSM0021622419, plan (intention)Name: Vysoce paralelní a distribuované výpočetní systémy
Investor: Ministry of Education, Youth and Sports of the CR, Highly Parallel and Distributed Computing Systems
MUNI/A/0914/2009, interní kód MUName: Rozsáhlé výpočetní systémy: modely, aplikace a verifikace (Acronym: SV-FI MAV)
Investor: Masaryk University, Category A
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