FIAMOLI, Veronika, Jan BLATNÝ, Ondřej ZAPLETAL, Světlana KÖHLEROVÁ and Eva JANOUŠOVÁ. Treatment of Deep Vein Thrombosis with Continuous IV Infusion of LMWH: A Retrospective Study in 32 Children. Thrombosis. Hindawi Publishing Corporation, 2011, Neuveden, February, p. "nestrankovano", 4 pp. ISSN 2090-1488. Available from: https://dx.doi.org/10.1155/2011/981497.
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Basic information
Original name Treatment of Deep Vein Thrombosis with Continuous IV Infusion of LMWH: A Retrospective Study in 32 Children
Authors FIAMOLI, Veronika (203 Czech Republic, guarantor, belonging to the institution), Jan BLATNÝ (203 Czech Republic, belonging to the institution), Ondřej ZAPLETAL (203 Czech Republic), Světlana KÖHLEROVÁ (203 Czech Republic) and Eva JANOUŠOVÁ (203 Czech Republic).
Edition Thrombosis, Hindawi Publishing Corporation, 2011, 2090-1488.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/11:00052823
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1155/2011/981497
Keywords in English deep vein thrombosis; LMWH; risk of thrombosis; antiXa
Changed by Changed by: RNDr. Eva Koriťáková, Ph.D., učo 184380. Changed: 31/1/2014 12:44.
Abstract
Thirty-two consecutive children aged 0–18 years with VTE treated with LMWH administered as a continuous infusion (CI) were identified at the Children’s University Hospital Brno. The treatment led to at least partial resolution of the thrombus within two weeks in 85% of patients. There were no adverse events or increased bleeding reported in any patients. No recurrences were observed during a followup period of 6 months. Although continuous infusion should not replace subcutaneous (SC) administration of LMWH, CI appeared to be safe and efficient and may provide an alternate method of administering LMWH in a subset of the paediatric population where SC administration may not be feasible. Further prospective studies are needed to support the promising findings of our pilot clinical observation.
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