IZAKOVIČOVÁ HOLLÁ, Lydie, Barbara HRDLIČKOVÁ, Jan VOKURKA and Antonín FASSMANN. Matrix metalloproteinase 8 (MMP8) gene polymorphisms in chronic periodontitis. Arch Oral Biol. Amsterodam: Elsevier, 2012, vol. 57, No 2, p. 188-196. ISSN 0003-9969. Available from: https://dx.doi.org/10.1016/j.archoralbio.2011.08.018.
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Basic information
Original name Matrix metalloproteinase 8 (MMP8) gene polymorphisms in chronic periodontitis
Name in Czech Polymorfizmy v genu pro matrix metaloproteinázu 8 (MMP8) u chronické parodontitidy
Authors IZAKOVIČOVÁ HOLLÁ, Lydie (203 Czech Republic, guarantor, belonging to the institution), Barbara HRDLIČKOVÁ (203 Czech Republic, belonging to the institution), Jan VOKURKA (203 Czech Republic, belonging to the institution) and Antonín FASSMANN (203 Czech Republic, belonging to the institution).
Edition Arch Oral Biol, Amsterodam, Elsevier, 2012, 0003-9969.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.549
RIV identification code RIV/00216224:14110/12:00059049
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.archoralbio.2011.08.018
UT WoS 000300801900010
Keywords (in Czech) genový polymorfizmus; MMPs; parodontitida; parodontální patogen
Keywords in English gene polymorphism; MMPs; periodontitis; periodontal pathogen
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 16/4/2013 15:49.
Abstract
Previous studies have suggested that some functional polymorphisms in the matrix metalloproteinase (MMPs) genes are associated with the risk of periodontal disease. However, to date no study has investigated MMP8 gene variants in relation to chronic periodontitis (CP). The aim of this study was to analyze polymorphisms in the MMP8 gene and their associations with microbial composition and clinical manifestation of CP.
Abstract (in Czech)
Dřívější studie poukázaly na roli funkčních polymorfizmů v genech pro matrix metaloproteinázy (MMPs)u onemocnění parodontu. Dosud však chybí práce, která by zkoumala genovou variabilitu u MMP8 ve vztahu k rozvoji chronické parodontitidy. Cílem naší práce bylo analyzovat vybrané polymorfizmy v MMP8 genu a jejich příp. asociace s mikrobiálním složením subgingiválního plaku a klinickou manifestací tohoto onemocnění.
Links
NT11405, research and development projectName: Mikrobiologické a genetické determinanty rozvoje a progrese parodontitidy u diabetiků 1. a 2. typu a jejich reciproční vztah ke kompenzaci diabetu
Investor: Ministry of Health of the CR
1M0528, research and development projectName: Stomatologické výzkumné centrum
Investor: Ministry of Education, Youth and Sports of the CR, Dental research centre
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