Další formáty:
BibTeX
LaTeX
RIS
@article{949977,
author = {Schubert, Ingo and Lysák, Martin},
article_number = {6},
doi = {http://dx.doi.org/10.1016/j.tig.2011.03.004},
keywords = {karyotype evolution; chromosome rearrangements; comparative genomics;},
language = {eng},
issn = {0168-9525},
journal = {Trends in Genetics},
title = {Interpretation of karyotype evolution should consider chromosome structural constraints},
volume = {27},
year = {2011}
}
TY - JOUR
ID - 949977
AU - Schubert, Ingo - Lysák, Martin
PY - 2011
TI - Interpretation of karyotype evolution should consider chromosome structural constraints
JF - Trends in Genetics
VL - 27
IS - 6
SP - 207-216
EP - 207-216
PB - Elsevier Trends Journals
SN - 01689525
KW - karyotype evolution
KW - chromosome rearrangements
KW - comparative genomics;
N2 - Comparative genetics, genomics and cytogenetics provide tools to trace the evolutionary history of extant genomes. Yet, the interpretation of rapidly increasing genomic data is not always done in agreement with constraints determined by chromosome structural features and by insights obtained from chromosome mutagenesis. The terms 'non-reciprocal chromosome translocation', 'chromosome fusion' and 'centromere shift' used to explain genomic differences among organisms are misleading and often do not correctly reflect the mechanisms of chromosome rearrangements underlying the evolutionary karyotypic variation. Here, we (re)interpret evolutionary genome alterations in a parsimonious way and demonstrate that results of comparative genomics and comparative chromosome painting can be explained on the basis of known primary and secondary chromosome rearrangements. Therefore, some widespread terms used in comparative and evolutionary genomics should be either avoided or redefined.
ER -
SCHUBERT, Ingo a Martin LYSÁK. Interpretation of karyotype evolution should consider chromosome structural constraints. \textit{Trends in Genetics}. Elsevier Trends Journals, 2011, roč.~27, č.~6, s.~207-216. ISSN~0168-9525. Dostupné z: https://dx.doi.org/10.1016/j.tig.2011.03.004.
|
