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@article{950085, author = {Křížková, S. and Zítka, O. and Masařík, Michal and Adam, V. and Stiborová, M. and Eckschlager, T. and Hubálek, J. and Kizek, R.}, article_number = {8}, keywords = {matrix metalloproteinases; clinical diagnostics; zymography; cancer}, language = {eng}, issn = {0006-9248}, journal = {Bratislavské lékařské listy}, title = {Clinical importance of matrix metalloproteinases}, volume = {112}, year = {2011} }
TY - JOUR ID - 950085 AU - Křížková, S. - Zítka, O. - Masařík, Michal - Adam, V. - Stiborová, M. - Eckschlager, T. - Hubálek, J. - Kizek, R. PY - 2011 TI - Clinical importance of matrix metalloproteinases JF - Bratislavské lékařské listy VL - 112 IS - 8 SP - 435-440 EP - 435-440 SN - 00069248 KW - matrix metalloproteinases KW - clinical diagnostics KW - zymography KW - cancer N2 - This review gives a brief summary on clinical applications of MMPs and their determination. Primarily, the activity of MMPs in cancer formation, development and metastasis is discussed. Further, survey on methods including fluorimetric methods, zymographies, Western-blotting, immunocapture assay, enzyme-linked immunosorbent assay, immunocytochemistry and immunohistochennistry, phage display, multiple-enzyme/multiple-reagent system, activity profiling, chronopotentiometric stripping analysis and imaging methods for detection and determination of MMPs follows (Fig. 3, Ref. 100). ER -
KŘÍŽKOVÁ, S., O. ZÍTKA, Michal MASAŘÍK, V. ADAM, M. STIBOROVÁ, T. ECKSCHLAGER, J. HUBÁLEK and R. KIZEK. Clinical importance of matrix metalloproteinases. \textit{Bratislavské lékařské listy}. 2011, vol.~112, No~8, p.~435-440. ISSN~0006-9248.
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