BALÁŽ, Marek, Martina BOČKOVÁ, Martin BAREŠ, Irena REKTOROVÁ, V. DÍREROVÁ and Ivan REKTOR. Kvalita života po hluboké mozkové stimulaci u pacientů s pokročilou Parkinsonovou nemocí (Quality of life after Deep Brain Stimulation in Patients with Advanced Parkinsons Disease). Česká a slovenská neurologie a neurochirurgie. vol. 74, No 5, p. 564-568. ISSN 1210-7859. 2011.
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Basic information
Original name Kvalita života po hluboké mozkové stimulaci u pacientů s pokročilou Parkinsonovou nemocí
Name (in English) Quality of life after Deep Brain Stimulation in Patients with Advanced Parkinsons Disease
Authors BALÁŽ, Marek (703 Slovakia, guarantor, belonging to the institution), Martina BOČKOVÁ (203 Czech Republic, belonging to the institution), Martin BAREŠ (203 Czech Republic, belonging to the institution), Irena REKTOROVÁ (203 Czech Republic, belonging to the institution), V. DÍREROVÁ (203 Czech Republic) and Ivan REKTOR (203 Czech Republic, belonging to the institution).
Edition Česká a slovenská neurologie a neurochirurgie, 2011, 1210-7859.
Other information
Original language Czech
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.279
RIV identification code RIV/00216224:14110/11:00053194
Organization unit Faculty of Medicine
UT WoS 000295020500009
Keywords (in Czech) hluboká mozková stimulace; kvalita života; Parkinsonova nemoc
Keywords in English deep brain stimulation; quality of life; Parkinsons disease
Tags International impact, Reviewed
Changed by Changed by: Mgr. Michal Petr, učo 65024. Changed: 12/2/2012 09:02.
Abstract
Cílem práce je popsat vliv hluboké mozkové stimulace subthalamického jádra na jednotlivé aspekty života pacientů s Parkinsonovou nemocí. Práce sleduje kvalitu života ve skupině 26 pacientů před operací, po 12 a 36 měsících od provedení hluboké mozkové stimulace. Kvalita života byla hodnocena pomocí dotazníku PDQ-39. Kavalita života pacientů se zlepšila o 46% po třech letech od operace. UPDRS III skóre se zlepšilo o 38% po jednom roce a o 31% po třech letech. V našem souboru jsme zjistili statisticky signifikantní zlepšení skóre PDQ-39 po 12 i 36 měsících od operace u všech pacientů. Nejvýrazněji se zlepšení odrazilo v motorických příznacích, které jsou DBS STN nejvíce ovlivněny. Lze pozorovat i efekt na sociální důsledky PArkinsonovy nemoci (stigma, sociální podpora, komunikace). Hluboká mozková stimulace má dlouhodobý efekt na kvalitu života.
Abstract (in English)
The object of the study was to describe the effect of deep brain stimulation of the subthalamic nucleus on various aspects of quality of life i patients with Parkinsons disease. Quality of life was asessed by means of the PDQ-39 questionnaire for 26 patients 12 and 36 months after deep brain stimulation to treat advanced Parkinsons disease. Patient quality of life, according to the PDQ-39 summary index, improved by 46% three years after surgery. UPDRS III scores improved by 39% in the fotrst year, and by 31% in the third year after DBS. We observed statistically significant improvements in quality of life for all patients both 13 and 36 months after deep brain stimulation. The improvement was most conspicuous in the motor subscales. However, benefit in the social aspects of Parkinsons disease (stigma, social support, communication) was also evident. Deep brain stimulation appears to have a long-lasting positive effect on the quality of life in patients with Parkinsons disease.
Links
MSM0021622404, plan (intention)Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.
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