Další formáty:
BibTeX
LaTeX
RIS
@article{952094, author = {Šustáčková, Gabriela and Kozubek, Stanislav and Stixová, Lenka and Legartová, Soňa and Matula, Pavel and Orlova, Darya Yurevna and Bártová, Eva}, article_location = {United States}, article_number = {5}, doi = {http://dx.doi.org/10.1002/jcp.22912}, keywords = {Polycomb body BMI1 protein arrangement confocal microscopy}, language = {eng}, issn = {0021-9541}, journal = {Journal of cellular physiology}, title = {Acetylation-dependent nuclear arrangement and recruitment of BMI1 protein to UV-damaged chromatin}, url = {http://onlinelibrary.wiley.com/doi/10.1002/jcp.22912/suppinfo}, volume = {227}, year = {2012} }
TY - JOUR ID - 952094 AU - Šustáčková, Gabriela - Kozubek, Stanislav - Stixová, Lenka - Legartová, Soňa - Matula, Pavel - Orlova, Darya Yurevna - Bártová, Eva PY - 2012 TI - Acetylation-dependent nuclear arrangement and recruitment of BMI1 protein to UV-damaged chromatin JF - Journal of cellular physiology VL - 227 IS - 5 SP - 1838-1850 EP - 1838-1850 PB - Wiley-Liss SN - 00219541 KW - Polycomb body BMI1 protein arrangement confocal microscopy UR - http://onlinelibrary.wiley.com/doi/10.1002/jcp.22912/suppinfo L2 - http://onlinelibrary.wiley.com/doi/10.1002/jcp.22912/suppinfo N2 - Polycomb group (PcG) proteins, organized into Polycomb bodies, are important regulatory components of epigenetic processes involved in the heritable transcriptional repression of target genes. Here, we asked whether acetylation can influence the nuclear arrangement and function of the BMI1 protein, a core component of the Polycomb group complex, PRC1. We used time-lapse confocal microscopy, micro-irradiation by UV laser (355 nm) and GFP technology to study the dynamics and function of the BMI1 protein. Our data indicate that the dynamics of recognition of UV-damaged chromatin, and the nuclear arrangement of BMI1 protein can be influenced by acetylation and occur as an early event prior to the recruitment of HPb to UV-irradiated chromatin. ER -
ŠUSTÁČKOVÁ, Gabriela, Stanislav KOZUBEK, Lenka STIXOVÁ, Soňa LEGARTOVÁ, Pavel MATULA, Darya Yurevna ORLOVA a Eva BÁRTOVÁ. Acetylation-dependent nuclear arrangement and recruitment of BMI1 protein to UV-damaged chromatin. \textit{Journal of cellular physiology}. United States: Wiley-Liss, 2012, roč.~227, č.~5, s.~1838-1850. ISSN~0021-9541. Dostupné z: https://dx.doi.org/10.1002/jcp.22912.
|