KRUPKOVÁ, Olga, Tomáš LOJA, Martina RÉDOVÁ, Jakub NERADIL, Karel ZITTERBART, Jaroslav ŠTĚRBA and Renata VESELSKÁ. Analysis of nuclear nestin localization in cell lines derived from neurogenic tumors. Tumor Biology. Springer, 2011, vol. 32, No 4, p. 631-639. ISSN 1010-4283.
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Basic information
Original name Analysis of nuclear nestin localization in cell lines derived from neurogenic tumors.
Authors KRUPKOVÁ, Olga (203 Czech Republic, belonging to the institution), Tomáš LOJA (703 Slovakia, belonging to the institution), Martina RÉDOVÁ (203 Czech Republic, belonging to the institution), Jakub NERADIL (203 Czech Republic, belonging to the institution), Karel ZITTERBART (203 Czech Republic, belonging to the institution), Jaroslav ŠTĚRBA (203 Czech Republic, belonging to the institution) and Renata VESELSKÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition Tumor Biology, Springer, 2011, 1010-4283.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher Germany
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.143
RIV identification code RIV/00216224:14310/11:00053485
Organization unit Faculty of Science
UT WoS 000292558600002
Keywords in English nestin;intermediate filaments;cytoskeleton;glioblastoma multiforme;neuroblastoma;medulloblastoma
Tags AKR, rivok
Tags International impact, Reviewed
Changed by Changed by: prof. RNDr. Renata Veselská, Ph.D., M.Sc., učo 1260. Changed: 2/4/2012 11:44.
Abstract
Using immunodetection methods, we examined nestin expression in tumor-derived cell lines obtained from 11 patients with neuroblastoma, medulloblastoma, or glioblastoma multiforme. Besides its standard cytoplasmic localization, nestin was present in the nuclei of two neuroblastoma cell lines and one medulloblastoma cell line.
Abstract (in Czech)
S využitím imunodetekčních metod byla prokázána exprese nestinu ve všech 11 buněčných liniích, derivovaných z nádorové tkáně pacientů s neuroblastomem, meduloblastomem nebo multiformním glioblastomem. Kromě standardní cytoplazmatické lokalizace byl nestin detekován i v buněčných jádrech u dvou neuroblastomových linií a jedné meduloblastomové linie.
Links
MSM0021622415, plan (intention)Name: Molekulární podstata buněčných a tkáňových regulací
Investor: Ministry of Education, Youth and Sports of the CR, Molecular basis of cell and tissue regulations
MUNI/A/0090/2009, interní kód MUName: Subcelulírní lokalizace nestinu v nádorově transformovaných buňkách
Investor: Masaryk University, Category A - centralized resources
NR9125, research and development projectName: Diagnostický a prediktivní význam molekulárně cytogenetických markerů u embryonálních nádorů dětského věku.
Investor: Ministry of Health of the CR
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