KOMÁREK, Jan, Josef HOUSER, Nikola KOSTLÁNOVÁ, Marie POKORNÁ, Anne IMBERTY and Michaela WIMMEROVÁ. Aspergillus fumigatus lectin – a new procedure for studying highly complex interactions of multivalent lectins with their ligands (Aspergillus fumigatus lectin – a new procedure for studying highly complex interactions of multivalent lectins with their ligands.). In YoungChem 2011. 2011. ISBN 978-83-61037-28-6.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Aspergillus fumigatus lectin – a new procedure for studying highly complex interactions of multivalent lectins with their ligands
Authors KOMÁREK, Jan (203 Czech Republic, belonging to the institution), Josef HOUSER (203 Czech Republic, belonging to the institution), Nikola KOSTLÁNOVÁ (203 Czech Republic, belonging to the institution), Marie POKORNÁ (203 Czech Republic, belonging to the institution), Anne IMBERTY (250 France) and Michaela WIMMEROVÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition YoungChem 2011, 2011.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 10600 1.6 Biological sciences
Country of publisher Poland
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14310/11:00050064
Organization unit Faculty of Science
ISBN 978-83-61037-28-6
Keywords (in Czech) lektiny; Aspergillus fumigatus
Keywords in English lectins; Aspergillus fumigatus
Tags International impact
Changed by Changed by: prof. RNDr. Michaela Wimmerová, Ph.D., učo 854. Changed: 13/1/2012 10:03.
Abstract
Lectins are proteins or glycoproteins of non-immune origin which recognize and bind reversibly to diverse sugar structures. They are involved in recognition events in a variety of physiological and pathological processes. One of the most interesting biological function of these sugar-specific proteins is their involvement in host-pathogen interactions. Wide range of pathogenic bacteria and viruses use their surface lectins (called adhesins) for recognition and adhesion to host tissues – in the the crucial step for initiation of infection. Inhibition of these lectins by suitable carbohydrates or their analogs might prevent attachment of pathogens to host cells and prevent the disease outbreak. Aspergillus fumigatus is an ubiquitous saprophytic mold and opportunistic pathogen responsible for severe infections in immuno-compromised individuals. The project is focused on a detailed characterization of L-fucose specific lectin AFL from A. fumigatus.
Links
GA303/09/1168, research and development projectName: Lektiny z lidských patogenů - struktura, funkce, inženýrství
Investor: Czech Science Foundation, Lectins from human pathogens - structure, function, engineering
MSM0021622413, plan (intention)Name: Proteiny v metabolismu a při interakci organismů s prostředím
Investor: Ministry of Education, Youth and Sports of the CR, Proteins in metabolism and interaction of organisms with the environment
PrintDisplayed: 19/7/2024 22:17