Detailed Information on Publication Record
2011
Kvantové tečky: příprava, konjugace a využití v bioanalytické chemii a biologii
HLAVÁČEK, Antonín and Petr SKLÁDALBasic information
Original name
Kvantové tečky: příprava, konjugace a využití v bioanalytické chemii a biologii
Name in Czech
Kvantové tečky: příprava, konjugace a využití v bioanalytické chemii a biologii
Name (in English)
The application of quantum dots in bioanalytical chemistry
Authors
HLAVÁČEK, Antonín (203 Czech Republic, belonging to the institution) and Petr SKLÁDAL (203 Czech Republic, guarantor, belonging to the institution)
Edition
Chemické listy, Praha, Česká společnost chemická, 2011, 0009-2770
Other information
Language
Czech
Type of outcome
Článek v odborném periodiku
Field of Study
10600 1.6 Biological sciences
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 0.529
RIV identification code
RIV/00216224:14310/11:00053898
Organization unit
Faculty of Science
UT WoS
000294274800006
Keywords (in Czech)
QD; fluorescenční značka. biokonjugát
Keywords in English
QD; fluorescent label; bioconjugate
Změněno: 13/11/2011 21:00, prof. RNDr. Petr Skládal, CSc.
V originále
biologické aplikace - review. Příklady syntézy, modifikace, konjugace a použití.
In English
Quantum dots (QD) are a novel type of nanoparticles used for fluorescent labeling of biomolecules. This review explains the structure, physical properties and synthesis of colloidal quantum dots. Bioconjugation strategies deve- loped in the last ten years are reviewed. Applicability of QDs in biomolecule labeling in bioanalytical chemistry and biology is described and compared with the routinely used organic fluorophores. However, a number of prob- lems have to be solved to achieve this goal, including de- velopment of robust protocols for QD bioconjugation, characterization of bioconjugates, and reduction of micro- organism toxicity. A promising field for application of QDs is the development of fluorescence- coded micropar- ticles (quantum dot bar code) which allow simultaneous detection of tens or hundreds of target analytes in the sam- ple. This inventive step leads to the development of porta- ble analyzers of DNA and protein markers.
Links
| MSM0021622413, plan (intention) |
|