HLAVÁČEK, Antonín and Petr SKLÁDAL. Kvantové tečky: příprava, konjugace a využití v bioanalytické chemii a biologii (The application of quantum dots in bioanalytical chemistry). Chemické listy. Praha: Česká společnost chemická, 2011, vol. 105, No 8, p. 611-615. ISSN 0009-2770.
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Basic information
Original name Kvantové tečky: příprava, konjugace a využití v bioanalytické chemii a biologii
Name in Czech Kvantové tečky: příprava, konjugace a využití v bioanalytické chemii a biologii
Name (in English) The application of quantum dots in bioanalytical chemistry
Authors HLAVÁČEK, Antonín (203 Czech Republic, belonging to the institution) and Petr SKLÁDAL (203 Czech Republic, guarantor, belonging to the institution).
Edition Chemické listy, Praha, Česká společnost chemická, 2011, 0009-2770.
Other information
Original language Czech
Type of outcome Article in a journal
Field of Study 10600 1.6 Biological sciences
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.529
RIV identification code RIV/00216224:14310/11:00053898
Organization unit Faculty of Science
UT WoS 000294274800006
Keywords (in Czech) QD; fluorescenční značka. biokonjugát
Keywords in English QD; fluorescent label; bioconjugate
Tags AKR, rivok
Changed by Changed by: prof. RNDr. Petr Skládal, CSc., učo 2202. Changed: 13/11/2011 21:00.
Abstract
biologické aplikace - review. Příklady syntézy, modifikace, konjugace a použití.
Abstract (in English)
Quantum dots (QD) are a novel type of nanoparticles used for fluorescent labeling of biomolecules. This review explains the structure, physical properties and synthesis of colloidal quantum dots. Bioconjugation strategies deve- loped in the last ten years are reviewed. Applicability of QDs in biomolecule labeling in bioanalytical chemistry and biology is described and compared with the routinely used organic fluorophores. However, a number of prob- lems have to be solved to achieve this goal, including de- velopment of robust protocols for QD bioconjugation, characterization of bioconjugates, and reduction of micro- organism toxicity. A promising field for application of QDs is the development of fluorescence- coded micropar- ticles (quantum dot bar code) which allow simultaneous detection of tens or hundreds of target analytes in the sam- ple. This inventive step leads to the development of porta- ble analyzers of DNA and protein markers.
Links
MSM0021622413, plan (intention)Name: Proteiny v metabolismu a při interakci organismů s prostředím
Investor: Ministry of Education, Youth and Sports of the CR, Proteins in metabolism and interaction of organisms with the environment
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