Kvantové tečky: příprava, konjugace a využití v bioanalytické chemii a biologii
HLAVÁČEK, Antonín and Petr SKLÁDAL. Kvantové tečky: příprava, konjugace a využití v bioanalytické chemii a biologii (The application of quantum dots in bioanalytical chemistry). Chemické listy. Praha: Česká společnost chemická, 2011, vol. 105, No 8, p. 611-615. ISSN 0009-2770. |
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Original name | Kvantové tečky: příprava, konjugace a využití v bioanalytické chemii a biologii |
Name in Czech | Kvantové tečky: příprava, konjugace a využití v bioanalytické chemii a biologii |
Name (in English) | The application of quantum dots in bioanalytical chemistry |
Authors | HLAVÁČEK, Antonín (203 Czech Republic, belonging to the institution) and Petr SKLÁDAL (203 Czech Republic, guarantor, belonging to the institution). |
Edition | Chemické listy, Praha, Česká společnost chemická, 2011, 0009-2770. |
Other information | |
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Original language | Czech |
Type of outcome | Article in a journal |
Field of Study | 10600 1.6 Biological sciences |
Country of publisher | Czech Republic |
Confidentiality degree | is not subject to a state or trade secret |
Impact factor | Impact factor: 0.529 |
RIV identification code | RIV/00216224:14310/11:00053898 |
Organization unit | Faculty of Science |
UT WoS | 000294274800006 |
Keywords (in Czech) | QD; fluorescenční značka. biokonjugát |
Keywords in English | QD; fluorescent label; bioconjugate |
Tags | AKR, rivok |
Changed by | Changed by: prof. RNDr. Petr Skládal, CSc., učo 2202. Changed: 13/11/2011 21:00. |
Abstract |
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biologické aplikace - review. Příklady syntézy, modifikace, konjugace a použití. |
Abstract (in English) |
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Quantum dots (QD) are a novel type of nanoparticles used for fluorescent labeling of biomolecules. This review explains the structure, physical properties and synthesis of colloidal quantum dots. Bioconjugation strategies deve- loped in the last ten years are reviewed. Applicability of QDs in biomolecule labeling in bioanalytical chemistry and biology is described and compared with the routinely used organic fluorophores. However, a number of prob- lems have to be solved to achieve this goal, including de- velopment of robust protocols for QD bioconjugation, characterization of bioconjugates, and reduction of micro- organism toxicity. A promising field for application of QDs is the development of fluorescence- coded micropar- ticles (quantum dot bar code) which allow simultaneous detection of tens or hundreds of target analytes in the sam- ple. This inventive step leads to the development of porta- ble analyzers of DNA and protein markers. |
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MSM0021622413, plan (intention) | Name: Proteiny v metabolismu a při interakci organismů s prostředím |
Investor: Ministry of Education, Youth and Sports of the CR, Proteins in metabolism and interaction of organisms with the environment |
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