Novel laser desorption sample introduction methods for inductively coupled plasma mass spectrometry

PREISLER, Jan, Pavla FOLTYNOVÁ, Ondřej PEŠ, Tomáš VACULOVIČ and Viktor KANICKÝ. Novel laser desorption sample introduction methods for inductively coupled plasma mass spectrometry. In Colloquium Spectroscopicum Internationale XXXVII. 2011. ISBN 978-85-8006-046-1.

Basic information

• Original name: Novel laser desorption sample introduction methods for inductively coupled plasma mass spectrometry
• Name in Czech: Nové laserově desorpční metody pro vstup vzorku pro hmotnostní spektrometrii indukčně vázaného plazmatu
• Authors: PREISLER, Jan (203 Czech Republic, guarantor, belonging to the institution), Pavla FOLTYNOVÁ (203 Czech Republic, belonging to the institution), Ondřej PEŠ (203 Czech Republic, belonging to the institution), Tomáš VACULOVIČ (203 Czech Republic, belonging to the institution) and Viktor KANICKÝ (203 Czech Republic, belonging to the institution).
• Edition: Colloquium Spectroscopicum Internationale XXXVII, 2011.

Other information

• Original language: English
• Type of outcome: Conference abstract
• Field of Study: 10406 Analytical chemistry
• Country of publisher: Brazil
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14740/11:00050177
• Organization unit: Central European Institute of Technology
• ISBN: 978-85-8006-046-1
• Keywords in English: SALD; LDTV; ICP MS; mass spectrometry; inductively coupled plasma; laser diode
• Tags: rivok

Abstract

New methods for determination of trace elements in submicroliter sample volumes, substrate-assisted laser desorption (SALD) and laser diode thermal vaporization (LDTV) inductively-coupled plasma mass spectrometry (ICP-MS) are presented. In summary, the both SALD and LDTV ICP-MS are suitable for quantitative elemental analysis of low volume samples (typically 100-500 nL) and represent an alternative to nebulizers. Potential advantages are also easy archiving, transportation, option of prearranged calibration sets on substrate and high throughput due to minimization of memory effects. In addition, biological samples, such as metalloproteins or metal complexes can be analyzed in multiple detection modes (SALD ICP-MS, MALDI-MS or fluorescence) from the same sample, which can provide supplementary information, e.g. protein mass or identity.

Links

• ED1.1.00/02.0068, research and development project: Name: CEITEC - central european institute of technology
• GA203/09/1025, research and development project: Name: Multidetekční platforma pro mikrokolonové separace proteinů a peptidů

Investor: Czech Science Foundation, Multidetection platform for microcolumn separation of proteins and peptides

• MSM0021622411, plan (intention): Name: Studium a aplikace plazmochemických reakcí v neizotermickém nízkoteplotním plazmatu a jeho interakcí s povrchem pevných látek

Investor: Ministry of Education, Youth and Sports of the CR, Study and application of plasma chemical reactions in non-isothermic low temperature plasma and its interaction with solid surface

• MSM0021622412, plan (intention): Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)

Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)

• MSM0021622415, plan (intention): Name: Molekulární podstata buněčných a tkáňových regulací

Investor: Ministry of Education, Youth and Sports of the CR, Molecular basis of cell and tissue regulations