SZTURZ, Petr, Zdeněk ADAM, Mária KLINCOVÁ, Josef FEIT, Marta KREJČÍ, Luděk POUR, Lenka ZAHRADOVÁ, Vladimír VAŠKŮ, Roman HÁJEK and Jiří MAYER. Multiple Myeloma Associated IgA Pemphigus: Treatment With Bortezomib- and Lenalidomide-Based Regimen. Clinical Lymphoma, Myeloma & Leukemia. 2011, vol. 11, No 6, p. 517-520. ISSN 2152-2650. Available from: https://dx.doi.org/10.1016/j.clml.2011.06.014. |
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@article{962152, author = {Szturz, Petr and Adam, Zdeněk and Klincová, Mária and Feit, Josef and Krejčí, Marta and Pour, Luděk and Zahradová, Lenka and Vašků, Vladimír and Hájek, Roman and Mayer, Jiří}, article_number = {6}, doi = {http://dx.doi.org/10.1016/j.clml.2011.06.014}, keywords = {Autoimmunity; Bortezomib; IgA pemphigus; Lenalidomide; Multiple myeloma; Paraproteinemia}, language = {eng}, issn = {2152-2650}, journal = {Clinical Lymphoma, Myeloma & Leukemia}, title = {Multiple Myeloma Associated IgA Pemphigus: Treatment With Bortezomib- and Lenalidomide-Based Regimen}, volume = {11}, year = {2011} }
TY - JOUR ID - 962152 AU - Szturz, Petr - Adam, Zdeněk - Klincová, Mária - Feit, Josef - Krejčí, Marta - Pour, Luděk - Zahradová, Lenka - Vašků, Vladimír - Hájek, Roman - Mayer, Jiří PY - 2011 TI - Multiple Myeloma Associated IgA Pemphigus: Treatment With Bortezomib- and Lenalidomide-Based Regimen JF - Clinical Lymphoma, Myeloma & Leukemia VL - 11 IS - 6 SP - 517-520 EP - 517-520 SN - 21522650 KW - Autoimmunity KW - Bortezomib KW - IgA pemphigus KW - Lenalidomide KW - Multiple myeloma KW - Paraproteinemia N2 - Generally, monoclonal immunoglobulins do not bind an autologous antigen, except for some cases, when it causes immune damage to body’s own tissues. Vesiculopustulous dermatitis associated with immunoglobulin (Ig) A deposition in the epidermis represents an autoimmune skin manifestation of monoclonal gammopathy. It is commonly referred to as subcorneal pustular dermatosis type of IgA pemphigus.1 In our previous work, we reported on complete and long-term remission of multiple myeloma associated IgA pemphigus after treatment with a bortezomib (Velcade) based regimen.2 In this work, to our knowledge, we are the first to publish a convincing clinical remission and excellent drug tolerance of a subsequent lenalidomide (Revlimid) based regimen used in the same patient for management of the relapsed disease. ER -
SZTURZ, Petr, Zdeněk ADAM, Mária KLINCOVÁ, Josef FEIT, Marta KREJČÍ, Luděk POUR, Lenka ZAHRADOVÁ, Vladimír VAŠKŮ, Roman HÁJEK and Jiří MAYER. Multiple Myeloma Associated IgA Pemphigus: Treatment With Bortezomib- and Lenalidomide-Based Regimen. \textit{Clinical Lymphoma, Myeloma \&{} Leukemia}. 2011, vol.~11, No~6, p.~517-520. ISSN~2152-2650. Available from: https://dx.doi.org/10.1016/j.clml.2011.06.014.
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