Cognitive deficits in hospitalized and never hospitalized remitted unipolar depressive patients

PREISS, Marek, Hana PŘIKRYLOVÁ KUČEROVÁ, Jiří LUKAVSKÝ and Petr SOS. Cognitive deficits in hospitalized and never hospitalized remitted unipolar depressive patients. European Journal of Psychiatry. Zaragoza, vol. 24, No 3, p. 129-135. ISSN 0213-6163. 2010.

Basic information

• Original name: Cognitive deficits in hospitalized and never hospitalized remitted unipolar depressive patients
• Name in Czech: Kognitivní funkce u pacientů s unipolární depresivní poruchou
• Authors: PREISS, Marek (203 Czech Republic, guarantor, belonging to the institution), Hana PŘIKRYLOVÁ KUČEROVÁ (203 Czech Republic, belonging to the institution), Jiří LUKAVSKÝ (203 Czech Republic) and Petr SOS (203 Czech Republic).
• Edition: European Journal of Psychiatry, Zaragoza, 2010, 0213-6163.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30000 3. Medical and Health Sciences
• Country of publisher: Spain
• Confidentiality degree: is not subject to a state or trade secret
• Impact factor: Impact factor: 0.186
• RIV identification code: RIV/00216224:14110/10:00054371
• Organization unit: Faculty of Medicine
• UT WoS: 000208392000001
• Keywords (in Czech): Kognitivní funkce; průběh nemoci; hospitalizace; depresivní epizody; výsledek; remise
• Keywords in English: Cognitive function; Course of illness; Hospitalization; Major depressive episode; Outcome; Remission

Abstract

Background and Objectives: Little is known about the differences between patients managing depression on an outpatient basis as compared with hospitalized ones. This study investigated the performance of attention, executive function and verbal memory during remission from unipolar depressive episodes and compare patients with and without history of hospitalization. Methods: The sample of participants who had undergone one or more hospitalizations (hospitalized, N = 46) as well as in a sample without hospitalization (never hospitalized, N = 46) and controls (N = 92) were used. The Auditory Verbal Learning Test (AVLT) and the Trail Making Test (TMT) were administrated to test this hypothesis. Results and conclusion: The hospitalized sample had similar results in all four neuropsychological variables in comparison with the never hospitalized group, and both groups had some lower results in comparison with controls. In comparison with the controls, hospitalized sample had mean cognitive deficits of 34% (28-41%), the never hospitalized group had a mean of 20% (21-35%). Contrary to previous reports we have found no meaningful differences between the two patient groups.

Abstract (in Czech)

Je jen málo známo o rozdílech mezi depresivními pacienty léčených v ambulanci ve srovnání s hospitalizovanými. Tato studie zkoumala výkon pozornosti, výkonné funkce a verbální paměť během remise u ambulantních pacientů s unipolární depresivní epizodou a porovnávala je s pacienty, kteří nebyli hospitalizováni. Metody: Vzorek účastníků, kteří podstoupili jednu nebo více hospitalizací (hospitalizován, N = 46), stejně jako u vzorku bez hospitalizace (nikdy nehospitalizován, N = 46) a ovládací prvky (N = 92) byly použiy. Sluchové verbální učení Test (AVLT) a Trail Making test (TMT) testovaly tuto hypotézu. Výsledky a závěr: Hospitalizovaný vzorek měl podobné výsledky ve všech čtyřech neuropsychologických proměnných ve srovnání s nehospitalizovaným vzorkem pacientů.