| VÁCHA, Robert, F.J. MARTINEZ-VERACOECHEA a D. FRENKEL. Receptor-Mediated Endocytosis of Nanoparticles of Various Shapes. Online. Nano Lett. American Chemical Society, 2011, roč. 11, č. 12, s. 5391–5395. ISSN 1530-6984. Dostupné z: https://dx.doi.org/10.1021/nl2030213. [citováno 2024-04-24] |
Další formáty:
BibTeX
LaTeX
RIS
@article{963555,
author = {Vácha, Robert and MartinezandVeracoechea, F.J. and Frenkel, D.},
article_number = {12},
doi = {http://dx.doi.org/10.1021/nl2030213},
keywords = {Effective uptake; passive endocytosis; phospholipid membrane; nanoparticle shape; molecular dynamics},
language = {eng},
issn = {1530-6984},
journal = {Nano Lett},
title = {Receptor-Mediated Endocytosis of Nanoparticles of Various Shapes},
volume = {11},
year = {2011}
}
TY - JOUR
ID - 963555
AU - Vácha, Robert - Martinez-Veracoechea, F.J. - Frenkel, D.
PY - 2011
TI - Receptor-Mediated Endocytosis of Nanoparticles of Various Shapes
JF - Nano Lett
VL - 11
IS - 12
SP - 5391–5395
EP - 5391–5395
PB - American Chemical Society
SN - 15306984
KW - Effective uptake
KW - passive endocytosis
KW - phospholipid membrane
KW - nanoparticle shape
KW - molecular dynamics
N2 - Cellular uptake through endocytosis is crucial for drug delivery and nanomedicine. However, the conditions under which passive endocytosis (i.e., not ATP driven) takes place are not well understood. We report MD simulations of the passive uptake of ligand-coated nanoparticles with varying size, shape, coverage, and membrane-binding strength. We find that the efficiency of passive endocytosis is higher for spherocylindrical particles than for spheres and that endocytosis is suppressed for particles with sharp edges.
ER -
VÁCHA, Robert, F.J. MARTINEZ-VERACOECHEA a D. FRENKEL. Receptor-Mediated Endocytosis of Nanoparticles of Various Shapes. Online. \textit{Nano Lett}. American Chemical Society, 2011, roč.~11, č.~12, s.~5391–5395. ISSN~1530-6984. Dostupné z: https://dx.doi.org/10.1021/nl2030213. [citováno 2024-04-24]
|
