| BASAK, Grzegorz W., Gabor MIKALA, Zdeněk KORISTEK, Ozren JAKSIC, Sandra BASIC-KINDA, Andrea CEGLEDI, Marienn RETI, Tamas MASSZI, Jiří MAYER, Sebastian GIEBEL, Kai HUEBEL, Boris LABAR a Wieslaw WIKTOR-JEDRZEJCZAK. Plerixafor to rescue failing chemotherapy-based stem cell mobilization: it's not too late. Online. Leukemia & Lymphoma. 2011, roč. 52, č. 9, s. 1711-1719. ISSN 1042-8194. Dostupné z: https://dx.doi.org/10.3109/10428194.2011.578312. [citováno 2024-04-23] |
Další formáty:
BibTeX
LaTeX
RIS
@article{965676,
author = {Basak, Grzegorz W. and Mikala, Gabor and Koristek, Zdeněk and Jaksic, Ozren and BasicandKinda, Sandra and Cegledi, Andrea and Reti, Marienn and Masszi, Tamas and Mayer, Jiří and Giebel, Sebastian and Huebel, Kai and Labar, Boris and WiktorandJedrzejczak, Wieslaw},
article_number = {9},
doi = {http://dx.doi.org/10.3109/10428194.2011.578312},
keywords = {Stem cell mobilization; plerixafor; autologous stem cell transplantation; G-CSF},
language = {eng},
issn = {1042-8194},
journal = {Leukemia & Lymphoma},
title = {Plerixafor to rescue failing chemotherapy-based stem cell mobilization: it's not too late},
volume = {52},
year = {2011}
}
TY - JOUR
ID - 965676
AU - Basak, Grzegorz W. - Mikala, Gabor - Koristek, Zdeněk - Jaksic, Ozren - Basic-Kinda, Sandra - Cegledi, Andrea - Reti, Marienn - Masszi, Tamas - Mayer, Jiří - Giebel, Sebastian - Huebel, Kai - Labar, Boris - Wiktor-Jedrzejczak, Wieslaw
PY - 2011
TI - Plerixafor to rescue failing chemotherapy-based stem cell mobilization: it's not too late
JF - Leukemia & Lymphoma
VL - 52
IS - 9
SP - 1711-1719
EP - 1711-1719
SN - 10428194
KW - Stem cell mobilization
KW - plerixafor
KW - autologous stem cell transplantation
KW - G-CSF
N2 - Plerixafor can rescue the outcome of failing chemotherapy-based stem cell mobilization. However, the optimal time for plerixafor injection in this setting has not been determined. This was investigated by retrospective analysis of data from 48 mobilizations with plerixafor, chemotherapy, and granulocyte-colony stimulating factor (G-CSF). The required yield of 2.0 x 10(6) CD34+ cells/kg was collected from 71% of patients; the median total yield was 4.1 x 10(6) CD34+ cells/kg. Patients to whom plerixafor was administered late (>= 15 days) after chemotherapy, after a long duration (>= 13 days) of treatment with G-CSF, or when the white blood cell count was high (>= 20 x 10(9)/L) were mobilized as efficiently as other patients. Plerixafor was shown to rescue mobilizations at a comparable rate in patients with critically low levels of peripheral blood CD34+ cells (53/mL) and those with higher concentrations. These data suggest that late administration of plerixafor in the course of chemotherapy-based mobilization does not contribute to the failure of this strategy.
ER -
BASAK, Grzegorz W., Gabor MIKALA, Zdeněk KORISTEK, Ozren JAKSIC, Sandra BASIC-KINDA, Andrea CEGLEDI, Marienn RETI, Tamas MASSZI, Jiří MAYER, Sebastian GIEBEL, Kai HUEBEL, Boris LABAR a Wieslaw WIKTOR-JEDRZEJCZAK. Plerixafor to rescue failing chemotherapy-based stem cell mobilization: it's not too late. Online. \textit{Leukemia \&{} Lymphoma}. 2011, roč.~52, č.~9, s.~1711-1719. ISSN~1042-8194. Dostupné z: https://dx.doi.org/10.3109/10428194.2011.578312. [citováno 2024-04-23]
|
