J 2011

Paramutation of tobacco transgenes by small RNA-mediated transcriptional gene silencing

CRHÁK KHAITOVÁ, Lucie, Miloslava FOJTOVÁ, Kateřina KŘÍŽOVÁ, Jana LUNEROVÁ, Jaroslav FULNEČEK et. al.

Basic information

Original name

Paramutation of tobacco transgenes by small RNA-mediated transcriptional gene silencing

Authors

CRHÁK KHAITOVÁ, Lucie (203 Czech Republic, guarantor), Miloslava FOJTOVÁ (203 Czech Republic, belonging to the institution), Kateřina KŘÍŽOVÁ (203 Czech Republic), Jana LUNEROVÁ (203 Czech Republic), Jaroslav FULNEČEK (203 Czech Republic), Anna DEPICKER (56 Belgium) and Aleš KOVAŘÍK (203 Czech Republic)

Edition

Epigenetics, Austin, Landes Bioscience, 2011, 1559-2294

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

Genetics and molecular biology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 4.318

RIV identification code

RIV/00216224:14740/11:00054886

Organization unit

Central European Institute of Technology

UT WoS

000290203600015

Keywords in English

transcriptional gene silencing; transgene epialleles; DNA methylation; small RNA

Tags

Tags

International impact, Reviewed
Změněno: 13/4/2012 00:44, Olga Křížová

Abstract

V originále

It has been well established that trans-acting small RNAs guide promoter methylation leading to its inactivation and gene silencing at the transcriptional level (TGS).These features contrast with a non-methylated single copy transgenic locus that required several generations of contact with RNA silencing molecules to become imprinted in a stable epiallele.

Links

MSM0021622415, plan (intention)
Name: Molekulární podstata buněčných a tkáňových regulací
Investor: Ministry of Education, Youth and Sports of the CR, Molecular basis of cell and tissue regulations