Další formáty:
BibTeX
LaTeX
RIS
@article{969174,
author = {Nieters, Alexandra and Bracci, Paige M. and de Sanjose, Silvia and Becker, Nikolaus and Maynadie, Marc and Benavente, Yolanda and Foretová, Lenka and Cocco, Pierluigi and Staines, Anthony and Holly, Elizabeth A. and Boffetta, Paolo and Brennan, Paul and Skibola, Christine F.},
article_location = {United States},
article_number = {6},
doi = {http://dx.doi.org/10.1002/ijc.25420},
keywords = {lymphoma; TNFRSF5; CD40; polymorphism; epidemiology},
language = {eng},
issn = {0020-7136},
journal = {International Journal of Cancer},
title = {A functional TNFRSF5 polymorphism and risk of non-Hodgkin lymphoma, a pooled analysis},
volume = {128},
year = {2011}
}
TY - JOUR
ID - 969174
AU - Nieters, Alexandra - Bracci, Paige M. - de Sanjose, Silvia - Becker, Nikolaus - Maynadie, Marc - Benavente, Yolanda - Foretová, Lenka - Cocco, Pierluigi - Staines, Anthony - Holly, Elizabeth A. - Boffetta, Paolo - Brennan, Paul - Skibola, Christine F.
PY - 2011
TI - A functional TNFRSF5 polymorphism and risk of non-Hodgkin lymphoma, a pooled analysis
JF - International Journal of Cancer
VL - 128
IS - 6
SP - 1481-1485
EP - 1481-1485
PB - Wiley-Liss
SN - 00207136
KW - lymphoma
KW - TNFRSF5
KW - CD40
KW - polymorphism
KW - epidemiology
N2 - Interaction between CD40 and its ligand, CD154, has a key function in immune regulation. Recent experimental data support a role of deregulated CD40 signalling in lymphomagenesis. Data from earlier studies that are part of this pooling study implicate a functional polymorphism (-1C>T, rs1883832) in the TNFRSF5 gene encoding CD40 in the etiology of follicular lymphoma. Here, the association of this variant with non-Hodgkin lymphoma (NHL) risk was replicated in a European multicenter study of 855 NHL cases and 1,206 controls. In the combined analysis of 2,617 cases and 3,605 controls, carrying the TT genotype was associated with an increased risk for all NHL (OR = 1.4; p for linear trend = 0.00009), diffuse large B-cell lymphoma (OR = 1.6; p for linear trend = 0.002) and follicular lymphoma (OR 5 1.6; p for linear trend = 0.001). These data suggest a possible role of this functional polymorphism in lymphomas originating within the germinal center.
ER -
NIETERS, Alexandra, Paige M. BRACCI, Silvia DE SANJOSE, Nikolaus BECKER, Marc MAYNADIE, Yolanda BENAVENTE, Lenka FORETOVÁ, Pierluigi COCCO, Anthony STAINES, Elizabeth A. HOLLY, Paolo BOFFETTA, Paul BRENNAN a Christine F. SKIBOLA. A functional TNFRSF5 polymorphism and risk of non-Hodgkin lymphoma, a pooled analysis. \textit{International Journal of Cancer}. United States: Wiley-Liss, roč.~128, č.~6, s.~1481-1485. ISSN~0020-7136. doi:10.1002/ijc.25420. 2011.
|
