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@book{969557, author = {Gökbuget, N. and Bassan, R. and Dombret, H. and Doubek, Michael and Fielding, A.K. and Foà, R. and Giebel, S. and Hoelzer, D. and Martinelli, G. and Meloni, G. and Moicean, A.D. and Ottmann, O. and Piccaluga, P.P. and Ribera, J.M. and Rousselot, P. and Walewski, J.}, address = {Bremen – London – Boston}, edition = {1st edition}, keywords = {Acute lymphoblastic leukemia; targeted therapy; optimisation of chemotherapy}, language = {eng}, location = {Bremen – London – Boston}, isbn = {978-1-84815-178-9}, publisher = {UNI-MED Verlag AG}, title = {Recommendations of the European Working Group for Adult ALL}, year = {2011} }
TY - BOOK ID - 969557 AU - Gökbuget, N. - Bassan, R. - Dombret, H. - Doubek, Michael - Fielding, A.K. - Foà, R. - Giebel, S. - Hoelzer, D. - Martinelli, G. - Meloni, G. - Moicean, A.D. - Ottmann, O. - Piccaluga, P.P. - Ribera, J.M. - Rousselot, P. - Walewski, J. PY - 2011 TI - Recommendations of the European Working Group for Adult ALL VL - Unimed Science PB - UNI-MED Verlag AG CY - Bremen – London – Boston SN - 9781848151789 KW - Acute lymphoblastic leukemia KW - targeted therapy KW - optimisation of chemotherapy N2 - Acute lymphoblastic leukemia (ALL) is a malignant disease of lymphatic cells in the bone marrow or other organs of the lymphoid system with a number of unique features. Cure rates were improved in the past decades first in children and later in adults from less than 10% to 40-50% and even >50% in distinct subgroups. Important progress was also achieved in basic research, particularly in molecular genetics. The progress in terms of diagnosis and treatment of ALL has stemmed mainly from systematic clinical research by a number of cooperative study groups. It is based on optimisation of chemotherapy, stem cell transplantation, supportive care integrated in risk adapted treatment strategies and more recently complemented by approaches for targeted therapy. The book gives an overview on the current strategies for management of adult ALL including approaches to rare entities and specific situations. It represents the result of a structured consensus process conducted by the members of the European Working Group for Adult ALL. ER -
GÖKBUGET, N., R. BASSAN, H. DOMBRET, Michael DOUBEK, A.K. FIELDING, R. FOÀ, S. GIEBEL, D. HOELZER, G. MARTINELLI, G. MELONI, A.D. MOICEAN, O. OTTMANN, P.P. PICCALUGA, J.M. RIBERA, P. ROUSSELOT a J. WALEWSKI. \textit{Recommendations of the European Working Group for Adult ALL}. 1st edition. Bremen – London – Boston: UNI-MED Verlag AG. 208 s. Unimed Science. ISBN~978-1-84815-178-9. 2011.
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