An epigenetic model for pigment patterning based on mechanical
and cellular interactions

J 2012

An epigenetic model for pigment patterning based on mechanical and cellular interactions

CABALLERO, Lorena, Mariana BENITEZ, Elena R. ALVAREZ-BUYLLA, Sergio HERNÁNDEZ, Alejandro V. ARZOLA et. al.

Basic information

Original name

An epigenetic model for pigment patterning based on mechanical and cellular interactions

Authors

CABALLERO, Lorena (484 Mexico), Mariana BENITEZ (484 Mexico, guarantor, belonging to the institution), Elena R. ALVAREZ-BUYLLA (484 Mexico), Sergio HERNÁNDEZ (484 Mexico), Alejandro V. ARZOLA (484 Mexico) and Germinal COCHO (484 Mexico)

Edition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Hoboken, Wiley, 2012, 1552-5007

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10602 Biology , Evolutionary biology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Full Text

Impact factor

Impact factor: 2.123

RIV identification code

RIV/00216224:14740/12:00059294

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1002/jez.b.22007

UT WoS

000303313800007

Keywords in English

pigment patterning; mechanical fields; epigenetics

Abstract

V originále

Pigment patterning in animals generally occurs during early developmental stages and has ecological, physiological, ethological, and evolutionary significance. Despite the relative simplicity of color patterns, their emergence depends upon multilevel complex processes. Thus, theoretical models have become necessary tools to further understand how such patterns emerge. Recent studies have reevaluated the importance of epigenetic, as well as genetic factors in developmental pattern formation. Yet epigenetic phenomena, specially those related to physical constraints that might be involved in the emergence of color patterns, have not been fully studied. In this article, we propose a model of color patterning in which epigenetic aspects such as cell migration, celltissue interactions, and physical and mechanical phenomena are central. This model considers that motile cells embedded in a fibrous, viscoelastic matrixmesenchymecan deform it in such a way that tension tracks are formed. We postulate that these tracks act, in turn, as guides for subsequent cell migration and establishment, generating long-range phenomenological interactions. We aim to describe some general aspects of this developmental phenomenon with a rather simple mathematical model. Then we discuss our model in the context of available experimental and morphological evidence for reptiles, amphibians, and fishes, and compare it with other patterning models. We also put forward novel testable predictions derived from our model, regarding, for instance, the localization of the postulated tension tracks, and we propose new experiments. Finally, we discuss how the proposed mechanism could constitute a dynamic patterning module accounting for pattern formation in many animal lineages

Links

LC06034, research and development project

Name: Regulace morfogeneze rostlinných buněk a orgánů

Investor: Ministry of Education, Youth and Sports of the CR, Regulation of morphogenesis of plant cells and organs

Citovat

CABALLERO, Lorena, Mariana BENITEZ, Elena R. ALVAREZ-BUYLLA, Sergio HERNÁNDEZ, Alejandro V. ARZOLA and Germinal COCHO. An epigenetic model for pigment patterning based on mechanical and cellular interactions. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution. Hoboken: Wiley, 2012, 318B, No 3, p. 209-223. ISSN 1552-5007. Available from: https://dx.doi.org/10.1002/jez.b.22007.

@article{970251,
   author = {Caballero, Lorena and Benitez, Mariana and AlvarezandBuylla, Elena R. and Hernández, Sergio and Arzola, Alejandro V. and Cocho, Germinal},
   article_location = {Hoboken},
   article_number = {3},
   doi = {http://dx.doi.org/10.1002/jez.b.22007},
   keywords = {pigment patterning; mechanical fields; epigenetics},
   language = {eng},
   issn = {1552-5007},
   journal = {Journal of Experimental Zoology Part B: Molecular and Developmental Evolution},
   title = {An epigenetic model for pigment patterning based on mechanical and cellular interactions},
   url = {http://onlinelibrary.wiley.com/doi/10.1002/jez.b.22007/abstract},
   volume = {318B},
   year = {2012}
}

TY  - JOUR
ID  - 970251
AU  - Caballero, Lorena - Benitez, Mariana - Alvarez-Buylla, Elena R. - Hernández, Sergio - Arzola, Alejandro V. - Cocho, Germinal
PY  - 2012
TI  - An epigenetic model for pigment patterning based on mechanical and cellular interactions
JF  - Journal of Experimental Zoology Part B: Molecular and Developmental Evolution
VL  - 318B
IS  - 3
SP  - 209-223
EP  - 209-223
PB  - Wiley
SN  - 15525007
KW  - pigment patterning
KW  - mechanical fields
KW  - epigenetics
UR  - http://onlinelibrary.wiley.com/doi/10.1002/jez.b.22007/abstract
L2  - http://onlinelibrary.wiley.com/doi/10.1002/jez.b.22007/abstract
N2  - Pigment patterning in animals generally occurs during early developmental stages and has ecological, physiological, ethological, and evolutionary significance. Despite the relative simplicity of color patterns, their emergence depends upon multilevel complex processes. Thus, theoretical models have become necessary tools to further understand how such patterns emerge. Recent studies have reevaluated the importance of epigenetic, as well as genetic factors in developmental pattern formation. Yet epigenetic phenomena, specially those related to physical constraints that might be involved in the emergence of color patterns, have not been fully studied. In this article, we propose a model of color patterning in which epigenetic aspects such as cell migration, celltissue interactions, and physical and mechanical phenomena are central. This model considers that motile cells embedded in a fibrous, viscoelastic matrixmesenchymecan deform it in such a way that tension tracks are formed. We postulate that these tracks act, in turn, as guides for subsequent cell migration and establishment, generating long-range phenomenological interactions. We aim to describe some general aspects of this developmental phenomenon with a rather simple mathematical model. Then we discuss our model in the context of available experimental and morphological evidence for reptiles, amphibians, and fishes, and compare it with other patterning models. We also put forward novel testable predictions derived from our model, regarding, for instance, the localization of the postulated tension tracks, and we propose new experiments. Finally, we discuss how the proposed mechanism could constitute a dynamic patterning module accounting for pattern formation in many animal lineages
ER  -

CABALLERO, Lorena, Mariana BENITEZ, Elena R. ALVAREZ-BUYLLA, Sergio HERNÁNDEZ, Alejandro V. ARZOLA and Germinal COCHO. An epigenetic model for pigment patterning based on mechanical and cellular interactions. \textit{Journal of Experimental Zoology Part B: Molecular and Developmental Evolution}. Hoboken: Wiley, 2012, 318B, No~3, p.~209-223. ISSN~1552-5007. Available from: https://dx.doi.org/10.1002/jez.b.22007.

Detailed Information on Publication Record