| STAESSEN, Jan, Lutgarde THIJS, Katarzyna STOLARZ-SKRZYPEK, A. BACCHIERI, John BARTON, Ezio ESPOSITI, Peter LEEUW, Mirosław DŁUŻNIEWSKI, Nicola GLORIOSO, Andrzej JANUSZEWICZ, Paolo MANUNTA, Viktor MILYAGIN, Yuri NIKITIN, Miroslav SOUČEK, Chiara LANZANI, Lorena CITTERIO, Mario TIMIO, Andrzej TYKARSKI, P. FERRARI, G. VALENTINI, K. KAWECKA-JASZCZ and G. BIANCHI. Main results of the Ouabain and Adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin. Trials. University of Oxford, 2011, vol. 12, No 13, p. "nestrankovano", 14 pp. ISSN 1745-6215. Available from: https://dx.doi.org/10.1186/1745-6215-12-13. |
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@article{971306,
author = {Staessen, Jan and Thijs, Lutgarde and StolarzandSkrzypek, Katarzyna and Bacchieri, A. and Barton, John and Espositi, Ezio and Leeuw, Peter and Dłużniewski, Mirosław and Glorioso, Nicola and Januszewicz, Andrzej and Manunta, Paolo and Milyagin, Viktor and Nikitin, Yuri and Souček, Miroslav and Lanzani, Chiara and Citterio, Lorena and Timio, Mario and Tykarski, Andrzej and Ferrari, P. and Valentini, G. and KaweckaandJaszcz, K. and Bianchi, G.},
article_number = {13},
doi = {http://dx.doi.org/10.1186/1745-6215-12-13},
keywords = {Hypertension; sodium; cardiovascular disease},
language = {eng},
issn = {1745-6215},
journal = {Trials},
title = {Main results of the Ouabain and Adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin},
volume = {12},
year = {2011}
}
TY - JOUR
ID - 971306
AU - Staessen, Jan - Thijs, Lutgarde - Stolarz-Skrzypek, Katarzyna - Bacchieri, A. - Barton, John - Espositi, Ezio - Leeuw, Peter - Dłużniewski, Mirosław - Glorioso, Nicola - Januszewicz, Andrzej - Manunta, Paolo - Milyagin, Viktor - Nikitin, Yuri - Souček, Miroslav - Lanzani, Chiara - Citterio, Lorena - Timio, Mario - Tykarski, Andrzej - Ferrari, P. - Valentini, G. - Kawecka-Jaszcz, K. - Bianchi, G.
PY - 2011
TI - Main results of the Ouabain and Adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin
JF - Trials
VL - 12
IS - 13
SP - "nestrankovano"
EP - "nestrankovano"
PB - University of Oxford
SN - 17456215
KW - Hypertension
KW - sodium
KW - cardiovascular disease
N2 - The Ouabain and Adducin for Specific Intervention on Sodium in Hypertension (OASIS-HT) Trial was a phase-2 dose-finding study of rostafuroxin, a digitoxygenin derivative, which selectively antagonizes the effects of endogenous ouabain (EO) on Na+,K+-ATPase and mutated adducin. Rostafuroxin lowered blood pressure (BP) in some animal models and in humans.
ER -
STAESSEN, Jan, Lutgarde THIJS, Katarzyna STOLARZ-SKRZYPEK, A. BACCHIERI, John BARTON, Ezio ESPOSITI, Peter LEEUW, Mirosław DŁU$\backslash$.ZNIEWSKI, Nicola GLORIOSO, Andrzej JANUSZEWICZ, Paolo MANUNTA, Viktor MILYAGIN, Yuri NIKITIN, Miroslav SOUČEK, Chiara LANZANI, Lorena CITTERIO, Mario TIMIO, Andrzej TYKARSKI, P. FERRARI, G. VALENTINI, K. KAWECKA-JASZCZ and G. BIANCHI. Main results of the Ouabain and Adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin. \textit{Trials}. University of Oxford, 2011, vol.~12, No~13, p.~''nestrankovano'', 14 pp. ISSN~1745-6215. Available from: https://dx.doi.org/10.1186/1745-6215-12-13.
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