J 2011

Involvement of the subthalamic nucleus and globus pallidus internus in attention

BOČKOVÁ, Martina, Jan CHLÁDEK, P. JURÁK, J. HALÁMEK, Marek BALÁŽ et. al.

Basic information

Original name

Involvement of the subthalamic nucleus and globus pallidus internus in attention

Authors

BOČKOVÁ, Martina (203 Czech Republic, guarantor, belonging to the institution), Jan CHLÁDEK (203 Czech Republic), P. JURÁK (203 Czech Republic), J. HALÁMEK (203 Czech Republic), Marek BALÁŽ (703 Slovakia, belonging to the institution) and Ivan REKTOR (203 Czech Republic, belonging to the institution)

Edition

JOURNAL OF NEURAL TRANSMISSION, 2011, 0300-9564

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

Austria

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.730

RIV identification code

RIV/00216224:14110/11:00055707

Organization unit

Faculty of Medicine

DOI

UT WoS

000293244800015

Keywords in English

Basal ganglia; ERP; ERD/S; Attention; DBS

Tags

International impact
Změněno: 2/8/2013 10:39, Ing. Mgr. Věra Pospíšilíková

Abstract

V originále

We studied the appearance of cognitive event-related potentials (ERPs) and event-related de/synchronizations (ERD/S) in the subthalamic nucleus (STN) and globus pallidus internus (GPi). We particularly focused on the rare non-target (distractor) stimuli processing. ERPs and ERD/S in the alpha and beta frequency range were analyzed in seven Parkinson's disease patients and one primary dystonia patient with implanted deep brain stimulation (DBS) electrodes. A visual three-stimulus protocol was used (frequent stimulus, target stimulus, and distractor). The non-target and distractor-related waveforms manifested similar shapes. A specific positive ERP peak around 200 ms and a low alpha frequency ERS were detected from the STN as a response to the distractor stimuli in six of the patients with Parkinson's disease and also in the primary dystonia patient's GPi. This positivity probably reflects an attentional orienting response to the distractor stimuli. The STN and GPi are probably involved in attentional cerebral networks.

Links

MSM0021622404, plan (intention)
Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.