Does repetitive transcranial magnetic stimulation have a positive effect on working memory and neuronal activation in treatment of negative symptoms of schizophrenia?

PŘIKRYL, Radovan, Michal MIKL, Hana PŘIKRYLOVÁ KUČEROVÁ, Libor USTOHAL, Tomáš KAŠPÁREK, Radek MAREČEK, Michaela VRZALOVÁ, Eva ČEŠKOVÁ and Jiří VANÍČEK. Does repetitive transcranial magnetic stimulation have a positive effect on working memory and neuronal activation in treatment of negative symptoms of schizophrenia? Neuroendocrinology Letters. Stockholm: MAGHIRA & MAAS PUBLICATIONS, 2012, vol. 33, No 1, p. 101-108. ISSN 0172-780X.

Basic information

• Original name: Does repetitive transcranial magnetic stimulation have a positive effect on working memory and neuronal activation in treatment of negative symptoms of schizophrenia?
• Name in Czech: Má opakující se transkraniální magnetická stimulace pozitivní vliv na pracovní paměť a nervové aktivace v léčbě negativních příznaků schizofrenie?
• Authors: PŘIKRYL, Radovan (203 Czech Republic, guarantor, belonging to the institution), Michal MIKL (203 Czech Republic, belonging to the institution), Hana PŘIKRYLOVÁ KUČEROVÁ (203 Czech Republic, belonging to the institution), Libor USTOHAL (203 Czech Republic, belonging to the institution), Tomáš KAŠPÁREK (203 Czech Republic, belonging to the institution), Radek MAREČEK (203 Czech Republic, belonging to the institution), Michaela VRZALOVÁ (203 Czech Republic, belonging to the institution), Eva ČEŠKOVÁ (203 Czech Republic, belonging to the institution) and Jiří VANÍČEK (203 Czech Republic, belonging to the institution).
• Edition: Neuroendocrinology Letters, Stockholm, MAGHIRA & MAAS PUBLICATIONS, 2012, 0172-780X.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30000 3. Medical and Health Sciences
• Country of publisher: Sweden
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Impact factor: Impact factor: 0.932
• RIV identification code: RIV/00216224:14740/12:00059379
• Organization unit: Central European Institute of Technology
• UT WoS: 000208852500016
• Keywords (in Czech): kognitivní funkce; fMRI; neuronální aktivace; negativní příznaky
• Keywords in English: cognitive functions; fMRI; neuronal activation; negative symptoms
• Tags: ok, rivok
• Tags: International impact, Reviewed

Abstract

Stimulation treatment led to a reduction of seriousness of negative schizophrenia symptoms in both comparative groups. However, mutual comparison of real (n=19) and sham (n=11) rTMS, respectively, has shown that the effect of real rTMS was statistically significantly higher compared with placebo stimulation. During stimulation treatment an improvement in working memory performance was also found. No statistically significant difference between the real and placebo sham rTMS, respectively, was established. The rate of neuronal activation did not change at all during rTMS treatment.

Links

• MSM0021622404, plan (intention): Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.

• NS9890, research and development project: Name: Funkční mozkové koreláty související s léčbou negativních příznaků schizofrenie repetitivní transkraniální magnetickou stimulací

Investor: Ministry of Health of the CR