J 2011

The Role of the Inferior Frontal Gyri in Cognitive Processing of Patients with Parkinson's Disease: A Pilot rTMS Study

SROVNALOVÁ, Hana, Radek MAREČEK and Irena REKTOROVÁ

Basic information

Original name

The Role of the Inferior Frontal Gyri in Cognitive Processing of Patients with Parkinson's Disease: A Pilot rTMS Study

Authors

SROVNALOVÁ, Hana (203 Czech Republic, guarantor, belonging to the institution), Radek MAREČEK (203 Czech Republic, belonging to the institution) and Irena REKTOROVÁ (203 Czech Republic, belonging to the institution)

Edition

MOVEMENT DISORDERS, 2011, 0885-3185

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 4.505

RIV identification code

RIV/00216224:14110/11:00055887

Organization unit

Faculty of Medicine

DOI

UT WoS

000293334800030

Keywords in English

Parkinsons disease; repetitive transcranial magnetic stimulation; cognitive; Stroop Test; Frontal Assessment Battery; inferior frontal gyrus

Tags

International impact
Změněno: 1/3/2012 11:17, Mgr. Michal Petr

Abstract

V originále

We studied whether 1 session of high-frequency repetitive transcranial magnetic stimulation (rTMS) applied sequentially over both the left and right inferior frontal gyri (IFG) would enhance performance in tests evaluating the ability to inhibit habitual responses (Stroop test, ST; Frontal Assessment Battery, FAB) in patients with Parkinson's disease (PD). Methods: Ten nondemented PD patients (6 men, 4 women; age, 66 +/- 6 years; disease duration, 5.4 +/- 2.45 years) entered the randomized, sham stimulation-controlled study with a crossover design. The ST and the FAB were performed prior to and immediately after an appropriate rTMS session. Results: The active but not sham rTMS induced significant improvement in all ST subtests (word, color, color-word). Conversely, the calculated Stroop interference and the FAB scores remained unchanged. Conclusions: In PD patients, rTMS of the IFG increased the speed of cognitive processing in both the congruent and incongruent conditions of the ST.

Links

MSM0021622404, plan (intention)
Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.