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@article{973670, author = {Rektorová, Irena}, article_number = {8}, doi = {http://dx.doi.org/10.1007/s00702-011-0674-x}, keywords = {Brain imaging; Executive; Memory; Mild cognitive impairment; Parkinsons disease}, language = {eng}, issn = {0300-9564}, journal = {Journal of Neural Transmission}, title = {Mild cognitive impairment exists in Parkinson's disease}, volume = {118}, year = {2011} }
TY - JOUR ID - 973670 AU - Rektorová, Irena PY - 2011 TI - Mild cognitive impairment exists in Parkinson's disease JF - Journal of Neural Transmission VL - 118 IS - 8 SP - 1179-1183 EP - 1179-1183 SN - 03009564 KW - Brain imaging KW - Executive KW - Memory KW - Mild cognitive impairment KW - Parkinsons disease N2 - Cognitive impairment exists in Parkinsons disease (PD) as a transitional state between cognitively intact and demented PD patients. It seems to be a risk factor for the development of dementia in PD, but the precise criteria and unfavorable cognitive profile of mild cognitive impairment in PD (MCI-PD) have not yet been established. The concept may turn to be different from that in Alzheimers disease since we search for those already diagnosed PD patients who are at risk of developing dementia. In addition, clinical variables specific for PD also play role. Importantly, MCI possesses a metabolic basis in PD. Various biomarkers particularly including neuropsychological testing and the brain imaging hold promise in identification of MCI-PD patients with unfavorable prognoses. Well-designed longitudinal studies in MCI-PD cohorts are needed to assess the sensitivity and specificity of the PD-MCI designation as far as dementia development is concerned. ER -
REKTOROVÁ, Irena. Mild cognitive impairment exists in Parkinson's disease. \textit{Journal of Neural Transmission}. 2011, vol.~118, No~8, p.~1179-1183. ISSN~0300-9564. Available from: https://dx.doi.org/10.1007/s00702-011-0674-x.
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