J 2011

Instrumental activities of daily living in Parkinson's disease dementia as compared with Alzheimer's disease: Relationship to motor disability and cognitive deficits: A pilot study

RAŠOVSKÁ, Hana and Irena REKTOROVÁ

Basic information

Original name

Instrumental activities of daily living in Parkinson's disease dementia as compared with Alzheimer's disease: Relationship to motor disability and cognitive deficits: A pilot study

Authors

RAŠOVSKÁ, Hana (203 Czech Republic, guarantor, belonging to the institution) and Irena REKTOROVÁ (203 Czech Republic, belonging to the institution)

Edition

Journal of the Neurological Sciences, 2011, 0022-510X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.353

RIV identification code

RIV/00216224:14110/11:00055892

Organization unit

Faculty of Medicine

DOI

UT WoS

000296927500061

Keywords in English

Parkinsons disease dementia; Alzheimers disease; Instrumental activities of daily living; Extrapyramidal symptoms; Cognitive functions

Tags

International impact
Změněno: 1/3/2012 11:47, Mgr. Michal Petr

Abstract

V originále

Our objective was to assess which clinical factors contribute most to the impairment of instrumental activities of daily living (IADL) in patients with dementia in Parkinsons disease (PDD) as compared to age- and dementia duration-matched patients with Alzheimer's disease (AD). Methods: Eighteen consecutive subjects (16 men, 2 women) with PDD and 30 age- and dementia duration-matched subjects with AD (13 men, 17 women) were recruited. The groups were not matched for their Mini-Mental Status Examination (MMSE) score. Neuropsychiatric, cognitive and motor data were collected in a routine clinical setting using the MMSE, four brief tests of the seven minute screen (i.e. the Benton Temporal Orientation, Grober and Buschkes enhanced cued recall, verbal fluency, and the clock drawing test), the Neuropsychiatric Inventory, a modified version of the Hoehn and Yahr scale and a Czech modified version of Lawton's IADL questionnaire. The IADL scores were correlated with clinical variables in each group. Results: There were no differences in IADL abilities between both groups. A significant association was found between IADL and cognitive impairment as measured by screening tests in the AD group. In the PDD group, IADL scores were particularly correlated with PD duration (r = -0.73, p<0.01) and the Hoehn and Yahr score (r = -0.59, p<0.01). Conclusion: Our pilot study results show that motor deficits remain the major contributor to IADL impairment in PDD.

Links

MSM0021622404, plan (intention)
Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.