HUSER, Martin, Jana ŽÁKOVÁ, Lenka ŠMARDOVÁ, Igor CRHA, Petr JANKŮ, Robert HUDEČEK and Pavel VENTRUBA. Combination of fertility preservation strategies in young women with recently diagnosed cancer. European Journal of Gynaecological Oncology. 2012, vol. 33, No 1, p. 42-50. ISSN 0392-2936.
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Basic information
Original name Combination of fertility preservation strategies in young women with recently diagnosed cancer
Authors HUSER, Martin (203 Czech Republic, guarantor, belonging to the institution), Jana ŽÁKOVÁ (203 Czech Republic), Lenka ŠMARDOVÁ (203 Czech Republic), Igor CRHA (203 Czech Republic), Petr JANKŮ (203 Czech Republic), Robert HUDEČEK (203 Czech Republic) and Pavel VENTRUBA (203 Czech Republic).
Edition European Journal of Gynaecological Oncology, 2012, 0392-2936.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30214 Obstetrics and gynaecology
Country of publisher Canada
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.577
RIV identification code RIV/00216224:14110/12:00064841
Organization unit Faculty of Medicine
UT WoS 000300253400007
Keywords in English Cancer; infenility; Fenility preservation; Oocyte cryopreservation: Ovariall tissue cryoprescrvation
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 22/4/2013 18:11.
Abstract
The study describes clinical management and outcomes of currently available fertility preservation techniques in a set of 154 young female cancer patients. Metlwds: Patients in reproductive age with newly diagnosed cancer were offered embryo or oocyte cryopreservation, ovarian tissue cryopreservation and the administration of GnRH analogues during chemotherapy. Particular attention was given to the technical aspects and clinical application of these fenility preservation techniques. Resuils: During the study period (2004-2009), 154 young female cancer patients were offered fertility preservation counseling. Patients average age was 29.4 years and average parity was 0.7 children. Administration of GnRH analogues and ovarian tissue cryopreservation were the most commonly used fertility preservation strategies. In 20 cases (16.1 %). the combination of several fertility preservation techniques was offered to individuaJly selected patients. Conclusions: Combination of fertility preservation techniques gives young cancer patients the best chance for future fertility and should be concentrated in specialized centers.
Links
NS9661, research and development projectName: Vliv metabolismu homocysteinu na poruchy plodnosti.
Investor: Ministry of Health of the CR
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