| SYCHROVÁ, Eliška, Tereza ŠTĚPÁNKOVÁ, Kateřina NOVÁKOVÁ, Luděk BLÁHA, J. P. GIESY and Klára HILSCHEROVÁ. Estrogenic activity in extracts and exudates of cyanobacteria and green algae. Environment International. OXFORD, ENGLAND: PERGAMON-ELSEVIER SCIENCE LTD, 2012, vol. 39, No 1, p. 134-140. ISSN 0160-4120. Available from: https://dx.doi.org/10.1016/j.envint.2011.10.004. |
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@article{975203,
author = {Sychrová, Eliška and Štěpánková, Tereza and Nováková, Kateřina and Bláha, Luděk and Giesy, J. P. and Hilscherová, Klára},
article_location = {OXFORD, ENGLAND},
article_number = {1},
doi = {http://dx.doi.org/10.1016/j.envint.2011.10.004},
keywords = {Cyanobacteria; Eutrophication; Endocrine disruption; Estrogenicity; Algae; Phytoplankton},
language = {eng},
issn = {0160-4120},
journal = {Environment International},
title = {Estrogenic activity in extracts and exudates of cyanobacteria and green algae.},
volume = {39},
year = {2012}
}
TY - JOUR
ID - 975203
AU - Sychrová, Eliška - Štěpánková, Tereza - Nováková, Kateřina - Bláha, Luděk - Giesy, J. P. - Hilscherová, Klára
PY - 2012
TI - Estrogenic activity in extracts and exudates of cyanobacteria and green algae.
JF - Environment International
VL - 39
IS - 1
SP - 134-140
EP - 134-140
PB - PERGAMON-ELSEVIER SCIENCE LTD
SN - 01604120
KW - Cyanobacteria
KW - Eutrophication
KW - Endocrine disruption
KW - Estrogenicity
KW - Algae
KW - Phytoplankton
N2 - Most exudates from cyanobacteria and algae were estrogenic with potencies expressed at 50% of the maximum response under control of the estrogen receptor ranging from 0.2 to 7.2 ng 17 beta-estradiol (E-2) equivalents (EEQ)/L. The greatest estrogenic potency was observed for common species Microcystis aerigunosa. Aqueous extracts of green algae and one species of cyanobacteria (Aphanizomenon gracile) elicited significant estrogenicity with EEQ ranging from 15 to 280 ng 17 beta-estradiol (E-2)/g dry weight. Scenedesmus quadricauda exudates and extracts of Aphanizomenon flos-aquae were antagonistic to the ER when coexposed to E2. The EEQ potency was not correlated with concentrations of cyanotoxins, such as microcystin and cylindrospermopsin, which suggests that the EEQ was comprised of other compounds. The study demonstrates some differences between the estrogenic potency of aqueous extracts prepared from the same species, but of different origin, while the effects of exudates were comparable within species.
ER -
SYCHROVÁ, Eliška, Tereza ŠTĚPÁNKOVÁ, Kateřina NOVÁKOVÁ, Luděk BLÁHA, J. P. GIESY and Klára HILSCHEROVÁ. Estrogenic activity in extracts and exudates of cyanobacteria and green algae. \textit{Environment International}. OXFORD, ENGLAND: PERGAMON-ELSEVIER SCIENCE LTD, 2012, vol.~39, No~1, p.~134-140. ISSN~0160-4120. Available from: https://dx.doi.org/10.1016/j.envint.2011.10.004.
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