Method of detoxication of yperite by using haloalkane dehalogenases

PROKOP, Zbyněk, Jiří DAMBORSKÝ, Filip OPLUŠTIL, Andrea FOŘTOVÁ and Yuji NAGATA. Method of detoxication of yperite by using haloalkane dehalogenases. 2012.

Basic information

• Original name: Method of detoxication of yperite by using haloalkane dehalogenases
• Authors: PROKOP, Zbyněk, Jiří DAMBORSKÝ, Filip OPLUŠTIL, Andrea FOŘTOVÁ and Yuji NAGATA.
• Edition: Number: IL 186596, Publisher: Israeli Patent Office, Place of publication: Israel, Owner's name: Masarykova univerzita, 2012.

Other information

• Original language: English
• Type of outcome: Patent
• Field of Study: 10600 1.6 Biological sciences
• Country of publisher: Israel
• Confidentiality degree: contents are subject to a state secret
• Organization unit: Faculty of Science
• Keywords in English: yperite; haloalkane dehalogenases

Abstract

*The method of detoxification of yperite by the use of haloalkane dehalogenases or their compositions, the method of preparation of dehalogenationating enzymes and of decontamination compositions which contain at least one wild type and/or modified haloalkane dehalogenase (EC 3.8.1.5) as an chemically active component. The preferred dehalogenases are DhaA from Rhodococcus rhodochrous NCIMB 13064, DmbA from Mycobacterium bovis 5033/66 or LinB from Sphingomonas paucimobilis UT26. Decontamination is utilized for detoxification of yperite from the surfaces of instrumentality, constructional objects, the people’s or animal’s skin and elements of environment, when yperite is exposed to the action of decontamination composition at +10 C to +70 C, preferably at +40 C and pH = 4 to 12.

Links

• MSM0021622412, plan (intention): Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)

Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)