FALTEJSKOVÁ, Petra, Marek SVOBODA, Klára ŠRŮTOVÁ, Jitka MLČOCHOVÁ, Andrej BEŠŠE, Jana NEKVINDOVÁ, Lenka RADOVÁ, Pavel FABIAN, Kateřina SLABÁ, Igor KISS, Rostislav VYZULA a Ondřej SLABÝ. Identification and functional screening of microRNAs highly deregulated in colorectal cancer. Online. Journal of Cellular and Molecular Medicine. Malden, USA: WILEY-BLACKWELL, 2012, roč. 16, č. 11, s. 2655-2666. ISSN 1582-1838. Dostupné z: https://dx.doi.org/10.1111/j.1582-4934.2012.01579.x. [citováno 2024-04-23] |
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@article{979332, author = {Faltejsková, Petra and Svoboda, Marek and Šrůtová, Klára and Mlčochová, Jitka and Bešše, Andrej and Nekvindová, Jana and Radová, Lenka and Fabian, Pavel and Slabá, Kateřina and Kiss, Igor and Vyzula, Rostislav and Slabý, Ondřej}, article_location = {Malden, USA}, article_number = {11}, doi = {http://dx.doi.org/10.1111/j.1582-4934.2012.01579.x}, keywords = {apoptosis; colorectal cancer; expression profilin; microRNA; migration}, language = {eng}, issn = {1582-1838}, journal = {Journal of Cellular and Molecular Medicine}, title = {Identification and functional screening of microRNAs highly deregulated in colorectal cancer}, url = {http://www.ncbi.nlm.nih.gov/pubmed/22469014}, volume = {16}, year = {2012} }
TY - JOUR ID - 979332 AU - Faltejsková, Petra - Svoboda, Marek - Šrůtová, Klára - Mlčochová, Jitka - Bešše, Andrej - Nekvindová, Jana - Radová, Lenka - Fabian, Pavel - Slabá, Kateřina - Kiss, Igor - Vyzula, Rostislav - Slabý, Ondřej PY - 2012 TI - Identification and functional screening of microRNAs highly deregulated in colorectal cancer JF - Journal of Cellular and Molecular Medicine VL - 16 IS - 11 SP - 2655-2666 EP - 2655-2666 PB - WILEY-BLACKWELL SN - 15821838 KW - apoptosis KW - colorectal cancer KW - expression profilin KW - microRNA KW - migration UR - http://www.ncbi.nlm.nih.gov/pubmed/22469014 L2 - http://onlinelibrary.wiley.com/doi/10.1111/j.1582-4934.2012.01579.x/pdf N2 - The aim of this study was to determine an expression profile of 667 miRNAs in CRC patients and paired non-tumoral tissues. We have identified 42 differentially expressed miRNAs and we have chosen 5 of them for further validation on an independent cohort of 125 CRC patients and in vitro analyses. Our results indicate that miR-378, miR-375, miR-422a and miR-215 play an important role in CRC as tumor suppressors, whereas miR-135b functions as an oncogene and all these miRNAs significantly contribute to the CRC pathogenesis. ER -
FALTEJSKOVÁ, Petra, Marek SVOBODA, Klára ŠRŮTOVÁ, Jitka MLČOCHOVÁ, Andrej BEŠŠE, Jana NEKVINDOVÁ, Lenka RADOVÁ, Pavel FABIAN, Kateřina SLABÁ, Igor KISS, Rostislav VYZULA a Ondřej SLABÝ. Identification and functional screening of microRNAs highly deregulated in colorectal cancer. Online. \textit{Journal of Cellular and Molecular Medicine}. Malden, USA: WILEY-BLACKWELL, 2012, roč.~16, č.~11, s.~2655-2666. ISSN~1582-1838. Dostupné z: https://dx.doi.org/10.1111/j.1582-4934.2012.01579.x. [citováno 2024-04-23]
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