Other formats:
BibTeX
LaTeX
RIS
@article{983340, author = {Máchalová, Alena and Šlais, Karel and Vrskova, Dagmar and Šulcová, Alexandra}, article_location = {Oxford, UK}, article_number = {2}, doi = {http://dx.doi.org/10.1016/j.pbb.2012.04.013}, keywords = {Psychostimulant; Modafinill; Methamphetamine; MDMA; Agnostic behavior; Mice}, language = {eng}, issn = {0091-3057}, journal = {Pharmacology Biochemistry and Behavior}, title = {Differential effects of modafinil, methamphetamine, and MDMA on agonistic behavior in male mice}, url = {http://www.sciencedirect.com/science/article/pii/S0091305712001232}, volume = {102}, year = {2012} }
TY - JOUR ID - 983340 AU - Máchalová, Alena - Šlais, Karel - Vrskova, Dagmar - Šulcová, Alexandra PY - 2012 TI - Differential effects of modafinil, methamphetamine, and MDMA on agonistic behavior in male mice JF - Pharmacology Biochemistry and Behavior VL - 102 IS - 2 SP - 215-223 EP - 215-223 PB - Elsevier Science Inc. SN - 00913057 KW - Psychostimulant KW - Modafinill KW - Methamphetamine KW - MDMA KW - Agnostic behavior KW - Mice UR - http://www.sciencedirect.com/science/article/pii/S0091305712001232 L2 - http://www.sciencedirect.com/science/article/pii/S0091305712001232 N2 - The aim of the present study was to compare the behavioral effects of modafinil, an atypical psychostimulatory acting and cognitive-function improving drug, with the effects of the psychostimulants methamphetamine (MET) and MDMA (3,4-methylenedioxymethamphetamine, or “ecstasy”) in a model of mouse agonistic behavior. This model enables the observation of ethologically well-defined sociable, timid, aggressive, and locomotor behavioral acts and postures. Singly-housed male mice (isolates)were separated into 4 groups. The observations were performed in 4 sessions, 1 week apart. In each interaction, singly-housed mice were paired with nonaggressive group-housed partners for 4 min in a neutral environment. The isolates received, in a Latin square design, either a) a vehicle or modafinil at doses 2.0, 10.0, or 50.0 mg/kg; or b) a vehicle or MET at doses 1.0, 5.0, or 10.0 mg/kg; or c) a vehicle or MDMA at doses 2.5, 10.0, or 30.0 mg/kg. The isolates were categorized as timid or aggressive according to their behavior in the control interaction (vehicle pre-treatment). Elements of locomotor, sociable, aggressive, and timid behavior were evaluated (one-way ANOVA). ER -
MÁCHALOVÁ, Alena, Karel ŠLAIS, Dagmar VRSKOVA and Alexandra ŠULCOVÁ. Differential effects of modafinil, methamphetamine, and MDMA on agonistic behavior in male mice. \textit{Pharmacology Biochemistry and Behavior}. Oxford, UK: Elsevier Science Inc., 2012, vol.~102, No~2, p.~215-223. ISSN~0091-3057. Available from: https://dx.doi.org/10.1016/j.pbb.2012.04.013.
|